Hydrogen: From a Biologically Inert Gas to a Unique Antioxidant

Liu, Shulin; Sun, Xuejun; Tao, Hengyi

doi:10.5772/34908

Cited by 5 publications

(5 citation statements)

References 44 publications

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“…body have recently been suggested, with molecular hydrogen being indicated as the fourth signaling gaseous molecule in the cell, in a manner similar to NO, CO and H 2 S [15,31,35]. As a signal transduction contributor, H 2 may regulate gene expressions and phosphorylations of several signal proteins, which is not casually associated with oxidative stress [23,25,27].…”

Section: Abstract ▼mentioning

confidence: 99%

“…Furthermore, molecular hydrogen might selectively scavenge the hydroxyl radical, the most cytotoxic of reactive oxygen species, while preserving other ROS (e. g. nitric oxide radical, hydrogen peroxide) important in cell physiology and homeostasis [19]. This emphasizes the importance of H 2 as a subtle ROS scavenger that discriminates between deleterious and beneficial ROS [31,41]. Through antioxidant-dependent power, molecular hydrogen may demonstrate anti-inflammatory, anti-apoptotic, and anti-allergic effects [8,10,16].…”

Section: Introduction ▼mentioning

confidence: 99%

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Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

Ostojić

2014

Int J Sports Med

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In the past 2 decades, molecular hydrogen emerged as a novel therapeutic agent, with antioxidant, anti-inflammatory and anti-apoptotic effects demonstrated in plethora of animal disease models and human studies. Beneficial effects of molecular hydrogen in clinical environment are observed especially in oxidative stress-mediated diseases, such as diabetes mellitus, brain stem infarction, rheumatoid arthritis, or neurodegenerative diseases. A number of more recent studies have reported that molecular hydrogen affects cell signal transduction and acts as an alkalizing agent, with these newly identified mechanisms of action having the potential to widen its application in clinical medicine even further. In particular, hydrogen therapy may be an effective and specific innovative treatment for exercise-induced oxidative stress and sports injury, with potential for the improvement of exercise performance. This review will summarize recent research findings regarding the clinical aspects of molecular hydrogen use, emphasizing its application in the field of sports medicine.

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Section: Abstract ▼mentioning

confidence: 99%

Section: Introduction ▼mentioning

confidence: 99%

Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

Ostojić

2014

Int J Sports Med

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“…That is, for every two molecules of re-formed water, 4 high-energy electrons are generated [9]. By other hand, the product of the water molecule dissociation with true value is molecular hydrogen [10], firstly: 98% of the universe is composed by Hydrogen, and secondly: Hydrogen is the quintessential carrier of energy in the entire universe, thus the metabolic reactions inside a eukaryotic cell should not be different from those occurring in the universe.…”

Section: Melanin Is the Human Chlorophyllmentioning

confidence: 99%

Neuron Cell Degeneration Results from Perturbed Mitochondria or <i>Vice Versa</i>?

Solís-Herrera¹,

Arias-Esparza²,

Solís-Arias³

2015

WJNS

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Mitochondrial disease has important implications for numerous functions that affect different cells lines and tissues. The mitochondrion is an organelle that draws much attention from researchers, but their study is hampered by changing in number, size, shape, and location among other things. To date, it is not understood if mitochondrial alterations could be considered to be downstream effects or are the root causes of diseases classified as neurodegenerative. It is an unresolved enigma if mitochondrion form, size, location, and number become crucial to the correct functioning of distinct cells lines and tissues, besides the role of reactive oxygen species (ROS) generated during the metabolism of glucose. The unexpected role of melanin to transform radiative energy directly into chemical energy by dissociation of the water molecule marks a milestone in the study of mitochondrial diseases.

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“…Such water is characterized by a low level of side effects, even with high concentrations of hydrogen, due to the absence of byproducts, unlike other known antioxidants. Hydrogen, interacting with the hydroxyl radical, forms a neutral water molecule, and no chain reactions or side chemical compounds are formed [14].…”

Section: Introductionmentioning

confidence: 99%

Influence of electrochemically activated water on the physical properties and rheological indicators of meat pates

Marynin

Pasichnyi

Shpak

et al. 2023

TAPR

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The object of research is the physical properties and rheological indicators of meat pates with corn starch suspensions prepared with activated water. Among the components of the composition of drinking water and food products, there are many substances with particularly inherent biological activity. The biological activity of water is caused by increased electronic or proton activity. Today, various ways of changing properties of water are known, but the most promising reagent-free method is the electrochemical activation of water. As a result of electrochemical treatment of water with an electric current, its electrochemical characteristics change. As a result, electrochemically activated aqueous solutions (catholyte/anolyte) are obtained; the water is saturated with oxygen, accelerates the removal of metabolic waste and promotes the most complete assimilation of nutrients. The research was aimed at determining the influence of activated water in the composition of starch suspensions on the physical properties and rheological indicators of meat pates with their content. Activated water affects the pH value of pates, which in the meat industry indicates the freshness and quality of meat raw materials and products made from them. Before pasteurization, the pH value for all samples was practically identical. That is, at the initial stage, activated water does not affect the acidity of pates. In the process of storage, the concentration of (H+) ions increases in pates, and the pH shifts to the acidic side. Water activity indicators of pates with starch suspensions on activated water gravitate towards the indicators of pates more than to the indicators of starch, the range for which is within 0.280–0.400. The dependence of the change in shear stress on the relaxation time of pates showed that regardless of the dosage of the starch suspension, the values of the shear stress of the samples on the catholyte in the time range 0–300 s are significantly higher than the values of the samples on the anolyte and tap water. This is explained by the ability of these samples, having acquired the necessary structure, to be less exposed to the external influence of deformation and to keep the structure more intact. The creep curves of all samples testify about the trimodal nature of the classical experimental creep curve. Thus, the electrochemical activation of water modifies the properties of corn starch and significantly affects the rheological indicators of meat pates containing it. The obtained results can be used in the development of recipes for meat pates and their production at enterprises.

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Hydrogen: From a Biologically Inert Gas to a Unique Antioxidant

Cited by 5 publications

References 44 publications

Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

Neuron Cell Degeneration Results from Perturbed Mitochondria or <i>Vice Versa</i>?

Influence of electrochemically activated water on the physical properties and rheological indicators of meat pates

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Hydrogen: From a Biologically Inert Gas to a Unique Antioxidant

Cited by 5 publications

References 44 publications

Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives

Neuron Cell Degeneration Results from Perturbed Mitochondria or &lt;i&gt;Vice Versa&lt;/i&gt;?

Influence of electrochemically activated water on the physical properties and rheological indicators of meat pates

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Product

Resources

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Neuron Cell Degeneration Results from Perturbed Mitochondria or <i>Vice Versa</i>?