Hydrogen-Bonded Chains in 4,4'-Dihydroxybenzophenone–4,4'-Bipyridyl (1/1) and Chains of Rings in 1,3,5-Trihydroxybenzene–4,4'-Bipyridyl (2/3)

Abstract

In the 1

4,4'-Bipyridyl at 203K

“…Although the crystal structure of the 4,4'-bipyridyl molecule, (I), has been reported many times in the context of acting as a Lewis base (e.g. Blake et al, 1997;Lu et al, 1997), or cocrystallized with hydrogen donors such as alcohols (Coupar et al, 1996;Sharma & Zawarotko, 1996) or transition metal complexes (Blake et al, 1997;Lu et al, 1997) to form macromolecular arrays (Coupar et al, 1996;Sharma & Zawarotko, 1996), the structure of the molecule itself has only been determined by electron diffraction (Almenningen & Bastiansen, 1958), although the structure of 3,3'-dimethyl-4,4'-bipyridyl has been reported (Gourdon, 1993).…”

Three concomitant polymorphs of 1 : 1 4,4′-dihydroxybenzophenone/1,2-bis(4-pyridyl)-ethylene: applications of hydrothermal method in searching polymorphs

“…When BPE is replaced by 4,49-bipyridine, only a 1 : 1 BIPY/ DHB{ single phase with space group C2/c has been obtained in the same hydrothermal conditions, which are similar to those prepared from methanol solution in common conditions. 11 This indicates that the observed three polymorphs in BPE/ DHB system could be related to the relative flexibility of BPE.…”

Supramolecular hydrogen-bonding patterns of co-crystals containing the active pharmaceutical ingredient (API) phloroglucinol andN-heterocycles

“…With the aim of gaining deeper insight into the PHL hydrogen-bonding capability, a search of the CSD (Groom et al, 2016) has been performed of all its co-crystals of known structure. Excluding disordered structures, 30 entries have been found (Santra & Biradha, 2011;Boldog et al, 2004;Haberhauer et al, 2004;Ung et al, 1994;Biradha & Zaworotko, 1998;Gao et al, 2008;Arora et al, 2009;Bis et al, 2007;Santra & Biradha, 2008;Sarma et al, 2008;Mahapatra et al, 2010;Lavender et al, 1998;Shi et al, 2010;Ghosh et al, 2005;Coupar et al, 1996;Barooah et al, 2003;Vishweshwar et al, 2003;Imai et al, 2009;Hou et al, 2010;Liu et al, 2001), two of which are simple solvated PHL [solvent: dimethylsulfoxide (Polyanskaya et al, 2011) and water (Thomas et al, 2011)]. The complete list of CSD entries, together with information on the co-crystals' composition and donorÁ Á Áacceptor distances of O-H(hydroxyl)Á Á ÁX interactions, considering only those in which the PHL hydroxyl group acts as a donor, are reported in Table S6 of the supporting information.…”

“…In six co-crystal structures, i.e. (5), HOPKAZ (Arora et al, 2009), MORVEV, MORVUL (Sarma et al, 2008), PUVMIC (Lavender et al, 1998), RAWDIC01 (Ghosh et al, 2005 and TEKKOJ (Coupar et al, 1996), the co-crystallized molecule has two (in one case, RAWDIC01, three) hydrogen-bonding acceptor groups, located on opposite sides. The 1:3 PHL-coformer stoichiometric ratio in this case is never observed, being 1:2 or 2:3.…”

“…Hydrogen-bonding motifs in CSD entries: (a) HIMGAL (coformer: 4-methylpyridine; Biradha & Zaworotko, 1998); (b) MORVOF (coformer: acridine; Sarma et al, 2008); (c) TEKKOJ (coformer: 4,4 0bipyridine; Coupar et al, 1996); (d) RAWDIC01 (coformer: urotropine;Ghosh et al, 2005).…”