Hydrogel-Based Drug Delivery for Lung Cancer

Sudhakar, Kalvatala; Mishra, Vijay; Riyaz, Bushra; Jain, Ankush; Charyulu, R. Narayana; Jain, Sanjay

doi:10.1016/b978-0-12-815720-6.00012-5

Cited by 6 publications

(2 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Poly(2hydroxyethyl methacrylate), or P-HEMA, was the first hydrogel to be created. Hydrogels can be cross-linked physically (via hydrogen bonding) or chemically (through ionic, covalent, and atomic bonding) [41].…”

Section: Nanocarrier Mediated Drug Delivery System [1] Liposomesmentioning

confidence: 99%

Developments in Nanotechnology for Lung Cancer Treatment: A Comprehensive Strategy

Khera,

Singh,

Deopa

2024

Int. J. Res. Publ. Rev.

View full text Add to dashboard Cite

Lung cancer is a significant worldwide health concern that demands novel approaches to its management. The field of nanotechnology has shown great promise for revolutionizing the treatment of this illness. An overview of the many applications of nanotechnology in lung cancer treatment is given in this abstract. For the treatment of lung cancer, drug delivery has been transformed using nanotechnology. Chemotherapy medicines can be specifically and precisely released at the tumor location by using nanoparticles that have been designed to encapsulate them. Patients receiving treatment benefit from this focused approach's dual benefits of minimizing systemic toxicity and increasing therapeutic effect, all of which improve patient quality of life. Furthermore, a major obstacle in the treatment of lung cancer is drug resistance, which nanoparticles help to overcome. The role of important receptors as well as the targeting types have also been discussed.Nanotechnology provides fresh ways to counter resistance mechanisms and boost treatment regimen efficacy through the creation of creative medication formulations and combination therapies.

show abstract

Section: Nanocarrier Mediated Drug Delivery System [1] Liposomesmentioning

confidence: 99%

Developments in Nanotechnology for Lung Cancer Treatment: A Comprehensive Strategy

Khera,

Singh,

Deopa

2024

Int. J. Res. Publ. Rev.

View full text Add to dashboard Cite

show abstract

“…Ethanol and propylene glycol/oleic acid are the main compounds for the penetration of transautosomes. Ethanol acts on corneodesmosomes and causes the release of corneocytes, thus making it easier to penetrate the skin layers, while penetration enhancers (surfactants or various agents) help to remove the barrier of the stratum corneum and loosen the dense protein structure and prepare the skin for more permeability makes drugs and vesicles more porous [ [94] , [95] , [96] , [97] ]. Probably, the synergy between ethanol and surfactant present in Transethosomes causes small size, excellent flexibility, and better permeability to the skin [ 84 , 98 ] and this vesicle can effectively pass through narrow intercellular pathways [ 40 ] and drug releases into the blood circulation, indicating a systemic effects.…”

Section: Introductionmentioning

confidence: 99%