2017
DOI: 10.1002/jctb.5367
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Hydrodynamic characteristics of an aerated coaxial mixing vessel equipped with a pitched blade turbine and an anchor

Abstract: Background In this work, computational fluid dynamics (CFD) simulation of an aerated coaxial mixing vessel composed of a centered impeller and a wall scraping anchor was conducted to investigate the effects of speed ratio, rotation modes (co‐rotating and counter‐rotating), and fluid viscosity on the local and global gas holdup values, flow pattern within the vessel, and turbulent kinetic energy. To validate the developed model, simulated gas holdup and gassed power uptake were compared with the measured experi… Show more

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Cited by 29 publications
(21 citation statements)
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“…The net torque or corrected torque ( M c ) was obtained from the subtraction of the residual torque, which was the torque achieved by rotating the impeller inside the empty tank, from the torque measured when the impeller was rotated in the gas–liquid mixture ( M m ). The total power consumption of the upper and lower shafts was obtained separately using the following equation 34‐37,42,43 P=2italicπNM …”
Section: Methodsmentioning
confidence: 99%
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“…The net torque or corrected torque ( M c ) was obtained from the subtraction of the residual torque, which was the torque achieved by rotating the impeller inside the empty tank, from the torque measured when the impeller was rotated in the gas–liquid mixture ( M m ). The total power consumption of the upper and lower shafts was obtained separately using the following equation 34‐37,42,43 P=2italicπNM …”
Section: Methodsmentioning
confidence: 99%
“…The system was divided into four zones namely two central impeller regions, a sparger region and an anchor region. To better capturing the complexity of the fluid near the central impellers, a smaller mesh size was executed for the central impellers regions along with seven layers of inflation 34,48 . After performing the grid independency test, the optimum number of cells was determined to be 2,018,467.…”
Section: Methodsmentioning
confidence: 99%
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“…It should be noted that, despite the popularity of CFD in the simulation of biotechnological apparatus, it needs to be validated by experimental data as there are some assumptions and simplified models in CFD. Depending on the desirable parameters to study, numerical simulations can be performed for a single phase [20], two phases [21], or three phases [22]. Kaiser et al [20] used single-phase CFD simulations in order to compare the flow pattern of the 2-litre single-use bioreactor and its reusable counterpart cell-culture bioreactors.…”
Section: Introductionmentioning
confidence: 99%