Hydrodynamic and Kinematic Study to Analyze the Mixing Efficiency of Short Passive Micromixers

Embarek, Douroum; Amar, Kouadri; Tahiri, Antar; Brihmat, Mostefa; Khelladi, Sofiane

doi:10.1021/acs.iecr.2c00084

Cited by 4 publications

(3 citation statements)

References 36 publications

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“…The mixing performance of the variable cross-sectional circular arc vortex micromixer is compared to that of the recently reported planar passive micromixer, as listed in Table , indicating that the micromixer in this work has superior mixing performance. This superiority in mixing performance is attributed to the combination of variable cross-sectional circular arc mixing chambers and jet channels. − …”

Section: Resultsmentioning

confidence: 99%

Multidirectional Vortex Micromixer Utilizing a Curved Channel with Variable Cross-Sectional Circular Arc Mixing Chambers

Xue,

Jin

2024

Ind. Eng. Chem. Res.

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A planar passive multidirectional vortex micromixer with a simple geometry and easy fabrication has been proposed and developed. The design of the microchannel structure integrates the flow impact, Dean flow, and vortex mixing effect by periodically arranging jet channels and variable cross-sectional circular arc mixing chambers. The complex vortex flow facilitates the breaking of the original laminar barrier of the fluid, which leads to efficient mixing by increasing the contact area of fluid mediums and reducing the diffusion distance of fluid molecules. The micromixer has been fabricated using precision micromilling technology, and the fluid mixing process was observed using a microscope imaging system. The fluid mixing process was simulated using commercial software, and the obtained numerical simulation results are consistent with the experimental results. At a flow Reynolds number of 70, the mixing index of the micromixer with a radius ratio of 2.66 is about 72% at the end of the first mixing module, and after completion of the flow of three mixing modules, the mixing index of its outlet channel cross section can reach more than 95%. This micromixer's simple and reliable performance makes it ideal for flexible applications in micro total analysis systems.

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Section: Resultsmentioning

confidence: 99%

Multidirectional Vortex Micromixer Utilizing a Curved Channel with Variable Cross-Sectional Circular Arc Mixing Chambers

Xue,

Jin

2024

Ind. Eng. Chem. Res.

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“…This fact evinces that an increase in the Reynolds number results in more intense secondary flows. Consequently, the fluid particles become more agitated, and the deformation of the fluid layers is favored [63]. It was clear from Figure 6 that the deformation rate increases as the Reynolds number and twisted angle do.…”

Section: Effect Of the Geometrical Factorsmentioning

confidence: 96%

Section: Effect Of the Geometrical Factorsmentioning

confidence: 99%

Exploring the Bioenergy Potential of Microfluidics: The Case of a T-Micromixer with Helical Elements for Sustainable Energy Solutions

Mahammedi,

Tayeb,

Rahmani

et al. 2023

Energies

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This study explores the potential application of microfluidics in the field of bioenergy, with a particular focus on the energy potential of biogas derived from vine shoots, a locally abundant waste material. The enhanced mixing capability of a micromixer has been analyzed to make it suitable for microfluidic energy applications. Mixing index, pressure drop, and kinematic measurements within the T-micromixer with helical elements and their related mixing performances have been studied and validated using CFD for different values of Reynolds number (0.1–60) for laminar Newtonian miscible fluid. Geometrical characteristics were further examined to improve the mixing performance. Various values of twisted angles were evaluated and compared to choose the optimal angle. A new parameter, Q, was introduced to represent the ratio of vorticity square over the sum of vorticity square and deformation square intensities. Furthermore, the results of the numerical simulation were compared with the given data in the literature, showing a significant agreement, in addition to the fact that a high-quality mixture can be created with a geometry angle of 90°, and a mixing index above 0.99 can be obtained at low Reynolds numbers. The numerical investigation of the flow regimes of miscible fluid in the T-microkenics with the proposed angle can be utilized to develop the mixing performance of the micromixers in a wide variety of processes.

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Machine learning and metaheuristics in microfluidic transport characterization and optimization: CFD and experimental study integrated with predictive modelling

Kouhkord,

Amirmahani,

Hassani

et al. 2024

Can J Chem Eng

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This study presents a comprehensive numerical and experimental analysis on microfluidic cell lysis through computational fluid dynamics (CFD), data‐driven modelling, and multi‐objective optimization. The proposed intelligent framework integrates artificial intelligence and CFD for data generation and extraction, alongside machine learning analysis and experimental studies for transport phenomena characterization in the cell lysis process. The framework explores compound effects of various inflow Reynolds numbers and geometrical parameters, including obstacle configurations and microchannel thickness. It shows substantial effects on flow patterns and mixing in varied microfluidic designs. A surrogate model, developed via central composite design, exhibits high accuracy in assessing system functionality (). The height of the implemented baffles from its lower value to the upper bound resulted in more than 42% and 14% increase in the mixing index at low and high Reynolds numbers, respectively, with minimal impact on pressure drop. The framework introduces data‐driven modelling coupled with multi‐objective optimization by desirability function (DF), non‐dominated sorting genetic algorithm (NSGA‐II), and differential evolution (DE). In the optimization of microfluidic processes, machine learning algorithms outperform desirability‐based methods, and the DE algorithm surpasses the NSGA‐II. An optimum micromixing reducing the mixing length by over 50% and mixing index above 97% achieved, fabricated, and experimental investigations conducted to validate numerical process. Through the precise control of microfluidic variables and the exploitation of microtransfer phenomena, it is possible to enhance the efficiency and selectivity of cell lysis. This not only improves the accuracy of diagnostic information but also opens up new avenues for personalized medicine and therapeutic development.

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Hydrodynamic and Kinematic Study to Analyze the Mixing Efficiency of Short Passive Micromixers

Cited by 4 publications

References 36 publications

Multidirectional Vortex Micromixer Utilizing a Curved Channel with Variable Cross-Sectional Circular Arc Mixing Chambers

Multidirectional Vortex Micromixer Utilizing a Curved Channel with Variable Cross-Sectional Circular Arc Mixing Chambers

Exploring the Bioenergy Potential of Microfluidics: The Case of a T-Micromixer with Helical Elements for Sustainable Energy Solutions

Machine learning and metaheuristics in microfluidic transport characterization and optimization: CFD and experimental study integrated with predictive modelling

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