Hydroalkylation of styrenes enabled by boryl radical mediated halogen atom transfer

Abstract

In this study, we present an inexpensive, stable, and easily available boryl radical source (NaBPh4) employed in a Halogen Atom Transfer (XAT) methodology. This mild and convenient strategy unlocks the...

Photoinduced Intermolecular Radical Hydroalkylation of Olefins via Ligated Boryl Radicals-Mediated Halogen Atom Transfer

“…However, concerns about the toxicity of organotin compounds and a recent emphasis on Green Chemistry have led to an ever-increasing interest in alternatives, preparing the ground for a transition from the Tyranny of Tin to the Democracy of Photons . In fact, visible-light photocatalysis has emerged as a milder technique for carbon-centered radical generation via XAT by silyl, α-aminoalkyl, and (ligated) boryl radicals . Alternative strategies for the generation of halogen abstractors have been devised as well, including an electrochemical manifold …”

“… 4 In fact, visible-light photocatalysis has emerged as a milder technique for carbon-centered radical generation via XAT by silyl, 5 α-aminoalkyl, 6 and (ligated) boryl radicals. 7 Alternative strategies for the generation of halogen abstractors have been devised as well, including an electrochemical manifold. 8 …”