Hydrazinium Monoformate: A New Hydrogen Donor. Selective Reduction of Nitrocompounds Catalyzed by Commercial Zinc Dust.

Abstract

Reduction ReductionO 0220 Hydrazinium Monoformate: A New Hydrogen Donor. Selective Reduction of Nitrocompounds Catalyzed by Commercial Zinc Dust. -The nitro group in compounds also containing reducible substituents is selectively and rapidly reduced under mild conditions to the corresponding amines (II) by employing the title reaction. -(GOWDA, S.; GOWDA, B. K. K.; GOWDA*, D. C.; Synth. Commun. 33 (2003) 2, 281-289; Dep. Stud. Chem., Univ. Mysore, Manasagangotri, Mysore 570 006, India; Eng.) -H. Haber 22-054

Effective and Reversible Capture of NH3 by Ethylamine Hydrochloride Plus Glycerol Deep Eutectic Solvents

“…However, they were found to be not available in the experimental temperature range of 200–300 K (see Figure S1). Therefore, the melting points of EaCl+Gly mixtures are much lower than those of pure EaCl (383 K) and pure Gly (291 K), validating that EaCl+Gly mixtures can be classified as DESs.…”

Synthesis, Biological Evaluation, and Structure–Activity Relationships of 2-[2-(Benzoylamino)benzoylamino]benzoic Acid Analogues as Inhibitors of Adenovirus Replication

“…For the four chlorinated compounds 32a , 32b , 32f , and 32g , reduction with hydrogen gas over palladium on charcoal resulted in the corresponding undesirable des -chloro compound. A small screen to find conditions that avoided reducing the chloro substitutent was carried out: NaBH 4 /Pd/C, SnCl 2 /2H 2 O, and FeCl 3 /C/hydrazine. − FeCl 3 /C/hydrazine conditions gave enough of the desired anilines 33f and 33g to move forward, although the method was less than ideal (20–46% yield). For nitro compounds 32a and 32b, with a methyl ester instead of an ethyl ester, no desired compound could be isolated.…”