2013
DOI: 10.2967/jnumed.112.105353
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Hybrid PET/MR Imaging of the Heart: Potential, Initial Experiences, and Future Prospects

Abstract: Learning Objectives: On successful completion of this activity, participants should be able to describe (1) advantages and shortcomings of hybrid PET/MR scanners with respect to cardiovascular applications (e.g. myocardial perfusion imaging and viability imaging), (2) additional value of the MR component in cardiac imaging, and (3) technical challenges and workflow considerations regarding hybrid PET/MR scanners in the field of cardiology (e.g. attenuation correction and cardiac/respiratory/patient motion).Fin… Show more

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Cited by 143 publications
(101 citation statements)
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References 90 publications
(100 reference statements)
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“…Recently, hybrid imaging of FDG‐PET and CMR has been applied for non‐invasive imaging of cardiac diseases 13. In particular, cardiac positron emission tomography–magnetic resonance imaging is reported to be clinically feasible for the detection of cardiac inflammation such as active CS 14…”
Section: Discussionmentioning
confidence: 99%
“…Recently, hybrid imaging of FDG‐PET and CMR has been applied for non‐invasive imaging of cardiac diseases 13. In particular, cardiac positron emission tomography–magnetic resonance imaging is reported to be clinically feasible for the detection of cardiac inflammation such as active CS 14…”
Section: Discussionmentioning
confidence: 99%
“…2) [8, 13,14]. One study reported on a patient with early interventional reperfusion after coronary artery occlusion that showed reduced glucose utilization in the perfusion territory of the culprit artery but did not show myocardial necrosis in terms of late gadolinium-enhancement.…”
Section: Acute Myocardial Infarctionmentioning
confidence: 99%
“…Among other things, this could be utilized as a success parameter in studies regarding cardioprotection. Other studies using PET/MRI have shown that after diet conversion of myocardial metabolism to fatty acid metabolism, the inflammatory reaction in the myocardial scar after myocardial infarction can be observed due to increased glucose utilization [14,16]; this could be used to guide new therapies to modulate infarct healing. Likewise, imaging of angiogenesis in the course of infarct healing uses special PET tracers such as αvβ3 Integrin; in the future this may result in additional applications of cardiac PET/ MRI [17].…”
Section: Acute Myocardial Infarctionmentioning
confidence: 99%
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“…The advent of hybrid positron emission tomography (PET)/magnetic resonance (MR) imaging systems has brought the potential of superior diagnostic performance over PET/CT (computed tomography) in certain applications, 1 , 2 , 3 , 4 , 5 including cardiac imaging 6 , 7 , 8 , 9 , 10 . However, respiratory motion can compromise the quantification of cardiac PET data using MR data.…”
Section: Introductionmentioning
confidence: 99%