Hybrid Nanoarchitectonics of Chitosan-Cerium Oxide Nanoparticles for Anticancer Potentials

Kermani, Golnar; Karimi, Ehsan; Tabrizi, Masoud Homayouni

doi:10.1007/s10904-022-02329-6

Cited by 7 publications

(2 citation statements)

References 44 publications

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“…For the human foreskin fibroblasts (HFF) and lung cell line (A549), the IC50 of ceria-loaded chitosan nanoparticles (CeCh-NPs) was reported to be 50.65 and 131.108 µg/mL, respectively [28]. According to a previous report, the median chitosan-cerium oxide nanoparticle concentrations against AGS, A459, PC3, and HFF cells were about 156.02, 169.1, 155.8, and 307.5 µg/mL, respectively [52]. In a study, after 48 h of incubation with varying concentrations of CeNPs (10 to 100 µg/mL), it was discovered that the cytotoxic effect of CeNPs on HaCaT (normal cell lines) and MCF-7 (cancer cell lines) suspended in Dulbecco's phosphate buffered saline (DPBS), with a pH of 7.4, is transient, dose-dependent, and depends on the type of cell lines [53].…”

Section: Anti-cancer Activity Of the Ceo2/cs/go Ternary Nanocomposite...mentioning

confidence: 99%

Development of Cerium Oxide/Chitosan/Graphene Oxide Nanocomposite: An Investigation toward Its Biological Applications under In Vitro Conditions

Saranya,

Preethi,

Shaik

et al. 2023

Crystals

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A ternary nanocomposite was prepared using cerium oxide, chitosan, and graphene oxide (CeO2/CS/GO) using a simple and cost-effective wet chemical method. The physicochemical properties of the developed ternary nanocomposite were examined using X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy with energy-dispersive X-ray spectroscopy, and ultraviolet-visible spectroscopy. Furthermore, the therapeutic behavior of the developed CeO2/CS/GO composite was assessed using anti-bacterial, anti-fungal, and anti-cancer assays. For Escherichia coli, Staphylococcus aureus, and Salmonella species, 750 µg/mL of the CeO2/CS/GO composite showed effective anti-bacterial activity, with a zone of inhibition of 9 mm. Additionally, the CeO2/CS/GO composite’s anti-fungal activity against Aspergillus niger was studied. The anti-cancer properties of different concentrations of the CeO2/CS/GO composite were assessed on MCF-7 cells, and 18.8% of cells were found to be viable at the maximum concentration of 1000 µg/mL CeO2/CS/GO and 46.37% at 125 µg/mL. The results of the hemolysis assay performed using human red blood cells and various concentrations of the CeO2/CS/GO composite indicated that the nanocomposite possesses biological properties. Overall, it can act as a therapeutic platform for breast cancer, bacterial and fungal infections.

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Section: Anti-cancer Activity Of the Ceo2/cs/go Ternary Nanocomposite...mentioning

confidence: 99%

Development of Cerium Oxide/Chitosan/Graphene Oxide Nanocomposite: An Investigation toward Its Biological Applications under In Vitro Conditions

Saranya,

Preethi,

Shaik

et al. 2023

Crystals

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“…Ederer et al (2019) reported on the destructive capability of nanoceria in degrading triphenyl phosphate pesticide, which begins by converting TTP to diphenyl phosphate and the final product phenol. Other applications of nanoceria include; the degradation of organophosphate pesticide fenchlorphos where the NPs serve as a reactive sorbent (Janoš et al, 2015), in-vitro skin decontamination of organophosphate pesticide (Salerno et al, 2017), electrochemical investigation of pantoprazole in the presence of epinephrine (Pradeepa & Nayaka, 2022), antimicrobial activity (Eka Putri et al, 2021), degradation of methylene blue dye (Kouser et al, 2021), degradation of phenol (Ahmad et al, 2020), degradation of rhodamine B dye, methyl orange dye and tetracycline (Li et al, 2018), anti-cancer potential (Kermani et al, 2022) and effective removal of uranium from aqueous solution (Kashyap et al, 2022). These and many other nanoceria applications attract researchers to explore the capabilities of cerium oxide nanoparticles (NPs).…”

Section: Introductionmentioning

confidence: 99%

Photocatalytic degradation and removal of type II pyrethroid pesticide (lambda-cyhalothrin) residue from wastewater using nanoceria for agricultural runoff application

Danjuma Sani,

Abbaraju,

Venugopal

2023

JANS

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Synthetic chemical pesticides' nature, mode of action, and persistence have brought about debates regarding whether the end justifies the means. Lambda-cyhalothrin is an important insecticide for farmers and households, with great accessibility and excellent action against pests and disease-carrying insects. Like other pyrethroid pesticides, Lambda-cyhalothrin targets the nervous system of insects or pests. However, its fate in the environment, especially in water and living systems, has made it crucial to explore methods of treating or degrading its residues in the environment. The present study aimed to develop a suitable method for the photocatalytic degradation and removal of Lambda-cyhalothrin (LCY) from wastewater and agricultural runoff. The nanoceria were used under natural solar irradiation without applying any scavenger chemical or buffer. This was synthesized using a simple co-precipitation method using cerium nitrate hexahydrate as a precursor. The synthesized nanoceria were characterized using X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDS), Fourier Transform Infrared spectroscopy (FTIR) and particle size analysis. The average size of the particle was 27 nm. The photocatalytic degradation was conducted in batches with various pesticide concentrations exposed to different amounts of nanoceria. The initial and final concentrations of the LCY at each level were determined using Shimadzu UV spectroscopy. At optimum conditions, nanoceria was found to degrade and remove more than 63% of the initial pesticide concentration. This method can be suitable for degrading and removing pesticide residue from agricultural runoff (at source) and industrial effluents from synthetic pesticide industries.

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Nanoarchitectonics, Method for Everything in Materials Science

Ariga

2022

J Inorg Organomet Polym

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Hybrid Nanoarchitectonics of Chitosan-Cerium Oxide Nanoparticles for Anticancer Potentials

Cited by 7 publications

References 44 publications

Development of Cerium Oxide/Chitosan/Graphene Oxide Nanocomposite: An Investigation toward Its Biological Applications under In Vitro Conditions

Development of Cerium Oxide/Chitosan/Graphene Oxide Nanocomposite: An Investigation toward Its Biological Applications under In Vitro Conditions

Photocatalytic degradation and removal of type II pyrethroid pesticide (lambda-cyhalothrin) residue from wastewater using nanoceria for agricultural runoff application

Nanoarchitectonics, Method for Everything in Materials Science

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