Hybrid Capture 2 Assay Based Evaluation of High-Risk HPV Status in Healthy Women of North-East India

Kumar, Avdhesh; Das, Debabrata; Kataki, Amal Chandra; Barmon, Debabrata; Aggarwal, Dippy; Deka, Pankaj; Shrivastava, Sushruta; Sharma, Jagannath Dev; Sarma, Anupam; Baruah, Upasana; Sharma, Manisha

doi:10.7314/apjcp.2014.15.2.861

Cited by 10 publications

(8 citation statements)

References 27 publications

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“…Considering population-based studies in which HC2 testing was used, the HC2-positive prevalence of 7.1% in our study is comparable to the reported prevalence from countries in Europe and North America (6.3-8.1%) (Cuzick et al, 2003;Leinonen et al, 2008;Castle et al, 2009;Ogilvie et al, 2012;Zorzi et al, 2013), while it is higher than the prevalence in the Netherlands (4.5%) (Bulkmans et al, 2007) but is lower than that in India (10.3-16.2%) (Sankaranarayanan et al, 2009;Pandey et al, 2012;Rai et al, 2014) and China (9.9-27.5%) (Zhao et al, 2010;Li et al, 2013). Population-based studies for HPV detection by PCR techniques also have demonstrated high overall HPV prevalence in Latin America and Africa, where cervical cancer incidence is high (Herrero et al, 2000;Franceschi et al, 2006).…”

Section: Discussionsupporting

confidence: 48%

Population-based Cervical Cancer Screening Using High-risk HPV DNA Test and Liquid-based Cytology in Northern Thailand

Siriaunkgul

Settakorn²,

Sukpan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Section: Discussionsupporting

confidence: 48%

Population-based Cervical Cancer Screening Using High-risk HPV DNA Test and Liquid-based Cytology in Northern Thailand

Siriaunkgul

Settakorn²,

Sukpan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…Moreover, discordance results from different type of linear array genotyping tests may occur (Rai et al, 2014). Our previous study showed that two linear array for HPV genotyping tests had discrepancy in results (Panigoro et al, 2013).…”

Section: Discussionmentioning

confidence: 98%

Human Papillomavirus Genotypes Profile in Cervical Cancer Patients at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Tobing

Sahiratmadja²,

Dinda³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: As in other developing countries, cervical cancer is the most frequent gynecologic malignancy in Indonesia. Persistent high risk genotypes of human papillomavirus (HPV) that infect the cervical tissue have been established as the etiology of cervical cancer. This study aimed to explore the profile of cervical cancer patients and the infected HPV genotypes at Dr. Hasan Sadikin General Hospital-Bandung. Materials and Methods: During the year 2010, 554 cervical cancer patients were registered. In a subset of the patients during July -November 2010, 40 randomized fresh biopsies were tested for HPV genotype after obtained informed consent. The distribution of HPV genotypes and the association to risk factors were analysed. Results: The result showed that 62.5% of the tested biopsies were infected by multiple HPV infections, with HPV-16 found in most of the cervical cancer patients (90%). Marriage at age younger than 16 years old was statistically significant in relation to multiple HPV infection (p=0.003), but not parity more than three times (p=0.59). Conclusions: Although high paritiy in our study was not associated with multiple HPV infection, good family planning programs and reproductive health education need to be emphasized in Indonesia as high parity and marriage at young age might increase the chance of cervical cancer development.

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“…More than 80% of the women diagnosed with cervical cancer live in the developing countries, such as China and Indian, the cervical cancer has been an important public health concern Rai et al, 2014). Several methods, such as visual inspection using acetic acid or Lugol's iodine, the conventional Pap smear and human papillomavirus (HPV) DNA testing, had been implemented for the screen of cervical cancer.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Genotype Distribution of Human Papillomavirus among Women from Henan, China

Wang

Sun²,

Ma³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Human papillomavirus (HPV) infection has been implicated as a causative of cervical cancer. In the present study, a total of 578 samples from females attending the gynecological outpatient clinic in Henan province, China, were collected and the HPV genotypes were detected by gene chip and flow-through hybridization. Overall, 44.5% (257/578) females were found to be HPV DNA positive, and the high risk HPV (HR-HPV) rate was 35.1% (203/578). The first peak of HR-HPV infection appeared in the >60 year-old group (55.0%), and the second was within the 51-55 year-old group (50.0%) (χ 2 =19.497, p<0.05). HPV 16 was the most prevalent genotype (9.2%), followed by HPV 52 (7.8%), HPV 6 (6.9%), HPV 11 (5.9%) and HPV 42 (5.0%). The single type HPV infection was 30.4%, with the five majority prevalent genotype HPV 16 (16.5%), HPV 52 (14.3%), HPV 6 (12.6%), HPV 42 (8.6%), HPV 31 (5.1%). The multiple-type HPV infections were 14.0%, and HPV 16 was the most prevalent type (29.6%), followed by HPV 52 (24.7%), HPV 6 (22.2%), HPV 11 (22.2%), HPV 42 (17.3%) and HPV 39 (17.3%).

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Hybrid Capture 2 Assay Based Evaluation of High-Risk HPV Status in Healthy Women of North-East India

Cited by 10 publications

References 27 publications

Population-based Cervical Cancer Screening Using High-risk HPV DNA Test and Liquid-based Cytology in Northern Thailand

Population-based Cervical Cancer Screening Using High-risk HPV DNA Test and Liquid-based Cytology in Northern Thailand

Human Papillomavirus Genotypes Profile in Cervical Cancer Patients at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Prevalence and Genotype Distribution of Human Papillomavirus among Women from Henan, China

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