Hybrid additive-subtractive femtosecond 3D manufacturing of nanofilter-based microfluidic separator

Andrijec, Dovilė; Andriukaitis, Deividas; Vargalis, Rokas; Baravykas, Tomas; Drevinskas, Tomas; Kornyšova, Olga; Butkuė, Agnė; Kaškonienė, Vilma; Stankevičius, Mantas; Gricius, Henrikas; Jagelavičius, Artūras; Maruška, Audrius; Jonušauskas, Linas

doi:10.1007/s00339-021-04872-4

Cited by 7 publications

(6 citation statements)

References 52 publications

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“…The surface quality criteria are one of the key disadvantages of femtosecond laser ablation. The technology performs in higher fabrication time but lacks in preserving sub-micron surface roughness [ 31 ]. The results of this investigation open a new discussion of the possibility to ablate structures with surface roughness values below 500 nm by employing bi-burst mode processing techniques.…”

Section: Results and Discussionmentioning

confidence: 99%

“…To demonstrate this difference visually, an example microfluidic channel was produced. It was manufactured either using non-burst ablation, with parameters specified in our previous works [ 31 ], or by using a newly discovered high-quality bi-burst methodology. In addition, we chose the T geometry channel to demonstrate the possibility to acquire sharp corners during processing.…”

Section: Results and Discussionmentioning

confidence: 99%

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Fabrication of Microfluidic Tesla Valve Employing Femtosecond Bursts

Andriukaitis

Vargalis²,

Šerpytis

et al. 2022

Micromachines

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Expansion of the microfluidics field dictates the necessity to constantly improve technologies used to produce such systems. One of the approaches which are used more and more is femtosecond (fs) direct laser writing (DLW). The subtractive model of DLW allows for directly producing microfluidic channels via ablation in an extremely simple and cost-effective manner. However, channel surface roughens are always a concern when direct fs ablation is used, as it normally yields an RMS value in the range of a few µm. One solution to improve it is the usage of fs bursts. Thus, in this work, we show how fs burst mode ablation can be optimized to achieve sub-µm surface roughness in glass channel fabrication. It is done without compromising on manufacturing throughput. Furthermore, we show that a simple and cost-effective channel sealing methodology of thermal bonding can be employed. Together, it allows for production functional Tesla valves, which are tested. Demonstrated capabilities are discussed.

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Section: Results and Discussionmentioning

confidence: 99%

Section: Results and Discussionmentioning

confidence: 99%

Fabrication of Microfluidic Tesla Valve Employing Femtosecond Bursts

Andriukaitis

Vargalis²,

Šerpytis

et al. 2022

Micromachines

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“…More information on setup and polymerization parameters can be found in our previous work [19]. Parameters and considerations used for channel cutting are described in a dedicated research study by our group [13].…”

Section: Methodsmentioning

confidence: 99%

“…This can be explained by their close proximity to the supporting channel walls. As channel walls can have significant deviations because of the fast cutting method [13], this translates to the valve walls being either deformed outward during fabrication or becoming seemingly thinner due to being partially inside the glass wall. However, as these only support structures, their deviations do not play an important role in the functionality of the device and seemingly would be much closer to the desired dimensions in the final device where channel walls are not present.…”

Section: Glass Channelmentioning

confidence: 99%

“…However, fs pulses used in MPP can also be used in much different processing regimes [10]. As was shown before, single fs direct laser writing (DLW) setup, consisting of a laser, positioning system, and optical chain, can be used for both subtractive and additive manufacturing in subsequent steps [11][12][13]. As a result, one way to potentially simplify MPP-made structure testing is to potentially integrate them in some other, bigger lasermade substrates, such as for instance, microchannels.…”

Section: Introductionmentioning

confidence: 99%

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Peculiarities of Integrating Mechanical Valves in Microfluidic Channels Using Direct Laser Writing

Hernandez-Cedillo

Andriukaitis

Šerpytis

et al. 2022

Applied Bionics and Biomechanics

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Regenerative medicine is a fast expanding scientific topic. One of the main areas of development directions in this field is the usage of additive manufacturing to fabricate functional components that would be later integrated directly into the human body. One such structure could be a microfluidic valve which could replace its biological counterpart in veins as it is worn out over the lifetime of a patient. In this work, we explore the possibility to produce such a structure by using multiphoton polymerization (MPP). This technology allows the creation of 3D structures on a micro- and nanometric scale. In this work, the fabrication of microfluidic systems by direct laser writing was carried out. These devices consist of a 100 μ m diameter channel and within it a 200 μ m long three-dimensional one-way mechanical valve. The idea of this device is to have a single flow direction for a fluid. For testing purposes, the valve was integrated into a femtosecond laser-made glass microfluidic system. Such a system acts as a platform for testing such small and delicate devices. Measurements of the dimensions of the device within such a testing platform were taken and the repeatability of this process was analyzed. The capability to use it for flow direction control is measured. Possible implications to the field of regenerative medicine are discussed.

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Laser-assisted fabrication of deterministic lateral displacement structures on P20 die steel masters for microfluidic particle separation

Pandit

Samuel

2022

Appl. Phys. A

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Hybrid additive-subtractive femtosecond 3D manufacturing of nanofilter-based microfluidic separator

Cited by 7 publications

References 52 publications

Fabrication of Microfluidic Tesla Valve Employing Femtosecond Bursts

Fabrication of Microfluidic Tesla Valve Employing Femtosecond Bursts

Peculiarities of Integrating Mechanical Valves in Microfluidic Channels Using Direct Laser Writing

Laser-assisted fabrication of deterministic lateral displacement structures on P20 die steel masters for microfluidic particle separation

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