Please cite this article as: J. Hua, L-X. An, Y-M. Li, Bionic fuzzy sliding mode control and robustness analysis, Appl. Math. Modelling (2014), doi: http://dx.Abstract: A bionic fuzzy sliding mode control based on switching control item fuzzification is proposed for a class of uncertain nonlinear systems. This article introduces the biological adaptation strategies into sliding mode control under uncertain boundary circumstance and disturbances. The trait of this new method is the design of switching-type control item in the sliding mode controller by utilizing the biological active adaptation strategies..Moreover, we analyze the robustness of bionic fuzzy sliding mode control system and prove the stability of the closed-loop system in the sense of Lyapunov. Finally, the simulation result for the circle of inverted-pendulum system is effective and feasible. it shows that the bionic fuzzy sliding mode control is superior to the conventional fuzzy sliding mode control. This way makes the chattering phenomenon in the sliding mode control was been alleviated and ensures that the tracking error steady be zero.