Abstract:Nowadays, there is a remarkable world trend in employing UAVs and drones for diverse applications. The main reasons are that they may cost fractions of manned aircraft and avoid the exposure of human lives to risks. Nevertheless, they depend on positioning systems that may be vulnerable. Therefore, it is necessary to ensure that these systems are as accurate as possible, aiming to improve navigation. In pursuit of this end, conventional Data Fusion techniques can be employed. However, its computational cost ma… Show more
“…1 ). The ratio of 8:2 is commonly used as a rule-of- thumb when splitting a dataset into training and test sets; a recent machine-learning study also reported that using 70% or 80% of the data as a training set showed the best result [ 15 ]. Fig.…”
Background
Almost all Koreans are covered by mandatory national health insurance and are required to undergo health screening at least once every 2 years. We aimed to develop a machine learning model to predict the risk of developing hepatocellular carcinoma (HCC) based on the screening results and insurance claim data.
Methods
The National Health Insurance Service-National Health Screening database was used for this study (NHIS-2020-2-146). Our study cohort consisted of 417,346 health screening examinees between 2004 and 2007 without cancer history, which was split into training and test cohorts by the examination date, before or after 2005. Robust predictors were selected using Cox proportional hazard regression with 1000 different bootstrapped datasets. Random forest and extreme gradient boosting algorithms were used to develop a prediction model for the 9-year risk of HCC development after screening. After optimizing a prediction model via cross validation in the training cohort, the model was validated in the test cohort.
Results
Of the total examinees, 0.5% (1799/331,694) and 0.4% (390/85,652) in the training cohort and the test cohort were diagnosed with HCC, respectively. Of the selected predictors, older age, male sex, obesity, abnormal liver function tests, the family history of chronic liver disease, and underlying chronic liver disease, chronic hepatitis virus or human immunodeficiency virus infection, and diabetes mellitus were associated with increased risk, whereas higher income, elevated total cholesterol, and underlying dyslipidemia or schizophrenic/delusional disorders were associated with decreased risk of HCC development (p < 0.001). In the test, our model showed good discrimination and calibration. The C-index, AUC, and Brier skill score were 0.857, 0.873, and 0.078, respectively.
Conclusions
Machine learning-based model could be used to predict the risk of HCC development based on the health screening examination results and claim data.
“…1 ). The ratio of 8:2 is commonly used as a rule-of- thumb when splitting a dataset into training and test sets; a recent machine-learning study also reported that using 70% or 80% of the data as a training set showed the best result [ 15 ]. Fig.…”
Background
Almost all Koreans are covered by mandatory national health insurance and are required to undergo health screening at least once every 2 years. We aimed to develop a machine learning model to predict the risk of developing hepatocellular carcinoma (HCC) based on the screening results and insurance claim data.
Methods
The National Health Insurance Service-National Health Screening database was used for this study (NHIS-2020-2-146). Our study cohort consisted of 417,346 health screening examinees between 2004 and 2007 without cancer history, which was split into training and test cohorts by the examination date, before or after 2005. Robust predictors were selected using Cox proportional hazard regression with 1000 different bootstrapped datasets. Random forest and extreme gradient boosting algorithms were used to develop a prediction model for the 9-year risk of HCC development after screening. After optimizing a prediction model via cross validation in the training cohort, the model was validated in the test cohort.
Results
Of the total examinees, 0.5% (1799/331,694) and 0.4% (390/85,652) in the training cohort and the test cohort were diagnosed with HCC, respectively. Of the selected predictors, older age, male sex, obesity, abnormal liver function tests, the family history of chronic liver disease, and underlying chronic liver disease, chronic hepatitis virus or human immunodeficiency virus infection, and diabetes mellitus were associated with increased risk, whereas higher income, elevated total cholesterol, and underlying dyslipidemia or schizophrenic/delusional disorders were associated with decreased risk of HCC development (p < 0.001). In the test, our model showed good discrimination and calibration. The C-index, AUC, and Brier skill score were 0.857, 0.873, and 0.078, respectively.
Conclusions
Machine learning-based model could be used to predict the risk of HCC development based on the health screening examination results and claim data.
“…1 ). The ratio of 7:3 is commonly used as a rule-of-thumb when splitting a dataset into training and test sets; a recent machine-learning study also reported that using 70% or 80% of the data as a training set showed the best result [ 17 ]. Fig.…”
Background
Early suspicion followed by assessing lung function with spirometry could decrease the underdiagnosis of chronic obstructive pulmonary disease (COPD) in primary care. We aimed to develop a nomogram to predict the FEV1/FVC ratio and the presence of COPD.
Methods
We retrospectively reviewed the data of 4241 adult patients who underwent spirometry between 2013 and 2019. By linear regression analysis, variables associated with FEV1/FVC were identified in the training cohort (n = 2969). Using the variables as predictors, a nomogram was created to predict the FEV1/FVC ratio and validated in the test cohort (n = 1272).
Results
Older age (β coefficient [95% CI], − 0.153 [− 0.183, − 0.122]), male sex (− 1.904 [− 2.749, − 1.056]), current or past smoking history (− 3.324 [− 4.200, − 2.453]), and the presence of dyspnea (− 2.453 [− 3.612, − 1.291]) or overweight (0.894 [0.191, 1.598]) were significantly associated with the FEV1/FVC ratio. In the final testing, the developed nomogram showed a mean absolute error of 8.2% between the predicted and actual FEV1/FVC ratios. The overall performance was best when FEV1/FVC < 70% was used as a diagnostic criterion for COPD; the sensitivity, specificity, and balanced accuracy were 82.3%, 68.6%, and 75.5%, respectively.
Conclusion
The developed nomogram could be used to identify potential patients at risk of COPD who may need further evaluation, especially in the primary care setting where spirometry is not available.
“…In the literature, there is a study that investigated the influence of the number of training periods on this data set. The study points out the methodology applied in the investigation was not an MLP but an approach using a Fuzzy system [26].…”
Section: Cross-validation Training -Hold Outmentioning
Over the past few years, there has been a steady increase in the use of aircraft vehicles, in particular unmanned aerial vehicles (UAV). UAV navigation is generally controlled by a human pilot. But the challenge for the scientific community is to carry out autonomous navigation. Some solutions have been proposed for the UAV autonomous navigation. Studies indicate as a solution to use data fusion and/or image processing navigation. Kalman Filter (KF) can be employed as a data fuser, but the KF has disadvantages. An alternative to the KF is based on artificial intelligence. Here, the KF is replaced by a self-configured neural network. This work investigates a way to select data for training the neural fuser, based on crossvalidation techniques. The results are compared to the data fusion done by a KF.
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