Abstract:Streptococcus pneumoniae (S. pneumoniae) is the leading cause of bacterial pneumonia in children and the elderly and it kills close to half a million children under 5 years old worldwide every year. Recent reports indicate that epithelial cells act not only as a physical barrier to pathogen invasion, but also as an extension of the immune system to prevent infection or eliminate pathogen. The herpes virus entry mediator (HVEM) is a member of the tumor necrosis factor (TNF) receptor super family. HVEM polymorph… Show more
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