Hürthle Cell Neoplasms of Thyroid in South-Western Region of Saudi Arabia

Al-Shraim, MM; Hussein, .; Musalam, AO; Alghamdi, Thamer; Alzahrani, Hassan; Mahfouz, AA; Sa, Abu-Eshy

doi:10.4314/wajm.v29i6.68275

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…(14,15) It allows easy and reliable sharing of data from different laboratories for national and international collaboration and comparison by establishing a common language. (14,15) There have been few studies validating the utility and diagnostic accuracy of FNA thyroid across different regions of Saudi Arabia, (5,(16)(17)(18)(19) to the knowledge of authors there are none reporting feedback on the application of the recently established system of TBSRTC within the context of the risk of thyroid malignancies among Saudi population. However several international studies and reviews have been published in this regard.…”

Section: Introductionmentioning

confidence: 99%

The Bethesda System for Reporting Thyroid Cytopathology : A Five-Year Retrospective Review of One Center Experience

Mufti¹,

Molah²

2012

IJHS

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Abstract:Fine-needle aspiration (FNA) of the thyroid gland is a widely accepted and accurate method for triaging patients with thyroid nodules. Thyroid FNA suffers from a reporting confusion due to multiplicity of category terminologies. To address this, The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) was recently introduced for unifying the terminology and morphologic criteria along with the corresponding risk of malignancy.Objective: The aim of this study was to report the diagnostic utility of TBSRTC at our institution and report the malignancy risk for FNA of thyroid lesions among Saudi patients using this system at KAUH (King Abdulaziz University Hospital), Jeddah, Saudi Arabia. Materials and methods: A retrospective study identifying 250 thyroid FNAs performed among Saudi patients between Jan 2005-Dec 2010 was undertaken. Cytology specimen data was collected through a computerized search of our cytopathology archives. Results: Among the 250 thyroid FNAs, 84 were followed by surgical resection. The overall surgical yield of malignancy was 23.8%. The malignancy rate for the 6 categories was as follows: non diagnostic: 20%, benign: 3.1%, atypia of undetermined significance: 50%, suspicious for follicular neoplasm: 20%, suspicious for malignancy: 80%, malignant: 100%. Conclusion:Retrospective classification of FNAs of thyroid lesions among Saudi patients using TBSRTC at KAAUH, Jeddah, Saudi Arabia, validates the diagnostic reproducibility of this system and yields similar results for risk of malignancy as reported by others. However the associated rates found for non diagnostic (20%) raise the possibility of malignancy risk in this category and validate the past observations that sample inadequacy is a common cause of false negative thyroid FNAs.

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Section: Introductionmentioning

confidence: 99%

The Bethesda System for Reporting Thyroid Cytopathology : A Five-Year Retrospective Review of One Center Experience

Mufti¹,

Molah²

2012

IJHS

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“…Few studies have validated the utility and diagnostic accuracy of FNA of thyroid nodules across Saudi Arabia, reported the risk of thyroid malignancies among the Saudi population, or provided feedback on TBSRTC after it was implemented in Saudi Arabia. In contrast, several international studies and reviews have been published on these topics in other countries [20][21][22][23][24][25][26][27].…”

Section: Introductionmentioning

confidence: 99%

Malignancy Risk for Fine-Needle Aspiration of Thyroid Nodules according to the Bethesda System for Reporting Thyroid Cytopathology, at King Abdul-Aziz, National Guard Hospital

Abdullah¹

2017

JOENTR

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Introduction: The Bethesda System was introduced to help us in risk of malignancy in reporting thyroid cytopathology. The Bethesda system is high predictive value of thyroid fine needle aspirates. FNA of the thyroid gland is an accurate method in our approach to manage our patient. Aim: The aim of this study was to determine the rates of malignancy of thyroid nodules in each standard cytologic diagnostic category of Bethesda system in our hospital. Materials and methods: A retrospective cross-sectional study in which all cases of thyroid nodules, presented to the OPC between September 2009 and August 2015 at King Abdulaziz NGHA. All preoperative cytologic examination by FNA and concurrent postoperative histopathologic examination were included. All FNA diagnoses were reclassified using the thyroid FNA Bethesda reporting system, including nondiagnostic, benign, atypical follicular lesion of undetermined significance, follicular/ hurthle cell neoplasm, suspicious for malignancy and malignant categories, the rate of malignancy based on final histopathologic evaluation was analyzed for each of these cytologic groups. Results: We reviewed 237 thyroid FNA samples and recorded interpretations according to the proposed standardized 6 categories and pursued follow-up cytology and histology. Of the 237 FNAs, 4.2% were nondiagnostic, 39.2% were benign, 15.6 % were AFLUS, 8.9 % were SFN, 16.9% were SM, and 15.2% were malignant. The rates of malignancy in histology were as follows: nondiagnostic, 0.0% benign, 4.3%; AFLUS, 18.9%; SFN 34 %: SM 95.0% and malignant, 94.4% Conclusion: The Bethesda system is a standardized system of reporting thyroid cytopathology, improving communication between cytopathologists and clinicians leading to ideal management approaches.

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Sonographic Features of Thyroid Nodules and Estimated Risk of Malignancy: A Comment

Ahmed

2022

IJAR

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Hürthle Cell Neoplasms of Thyroid in South-Western Region of Saudi Arabia

Abstract: WAJM 2010; 29 (6): 398-402.

Cited by 3 publications

References 14 publications

The Bethesda System for Reporting Thyroid Cytopathology : A Five-Year Retrospective Review of One Center Experience

The Bethesda System for Reporting Thyroid Cytopathology : A Five-Year Retrospective Review of One Center Experience

Malignancy Risk for Fine-Needle Aspiration of Thyroid Nodules according to the Bethesda System for Reporting Thyroid Cytopathology, at King Abdul-Aziz, National Guard Hospital

Sonographic Features of Thyroid Nodules and Estimated Risk of Malignancy: A Comment

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