Hürthle cell adenoma arising in a thyroglossal duct cyst

“…There are numerous case reports of malignant change within duct remnants, the commonest being thyroid papillary carcinoma. 6 Others include mixed papillary-follicular, 6 squamous cell, 7 follicular, 8 anaplastic, 6 Hü rthle cells adenomas 9 and carcinomas. 10 All tend to occur in older patients.…”

Section: Discussionmentioning

confidence: 99%

Thyroglossal duct remnants

Waddell¹,

Saleh²,

Robertson³

et al. 2000

J. Laryngol. Otol.

View full text Add to dashboard Cite

Thyroglossal duct remnants presenting as a lump in the neck are usually called thyroglossal cysts. Meticulous dissection of the cyst and duct, along with the body of the hyoid bone (Sistrunk's operation) is necessary to avoid recurrence. The authors have reviewed the histology of 61 consecutive specimens diagnosed preoperatively as thyroglossal cysts and have found that a true cyst exists in only 46 per cent of cases.

show abstract

“… 13 and Lyos et al . 14 each reported a case of Hürthle cell adenoma, while Adler and Freeman 15 reported a case of Hürthle cell carcinoma with frank vascular invasion. Our case is the third reported case of a Hürthle cell adenoma arising in a thyroglossal duct cyst, and is the first known case of Hürthle cell adenoma of the thyroglossal duct fistula.…”

Section: Discussionmentioning

confidence: 99%

“…Analogous to the currently preferred conservative management of thyroid tumors, the Sistrunk procedure, 16 with resection of the thyroglossal duct cyst, central portion of the hyoid, and thyroglossal duct to the foramen cecum at the base of the tongue, is well accepted, and has demonstrated success with a low recurrence rate. 14 …”

Section: Discussionmentioning

confidence: 99%

Hürthle cell adenoma of the thyroglossal duct fistula

et al. 1998

View full text Add to dashboard Cite

A 41‐year‐old man noted the presence of a punched‐out ulcer on the anterior midline of the neck. There was no previous history of trauma or radiation to the head and neck region. Physical examination showed a draining sinus surrounded by a cribriform scar on the anterior midline of the neck ( Fig. 1). There was no adenopathy in the neck. The head and neck were otherwise normal, as were T3 and T4, routine blood and urine tests, and chest X‐rays. Thyroid scan was performed which demonstrated normal uptake and normal location of the thyroid gland. Computed tomographic scan showed a 2.5×1.0×1.0‐cm‐sized ovoid, hypodense cystic mass extending to the cricoid cartilage. Because there was doubt as to the extent of the fistulous tract and its ramifications, a roentgen study of the tract after injection of a contrast medium was performed. The fistulogram showed that the injected contrast medium was observed at the base of the tongue through a faintly opacified thread‐like fistulous tract from the skin. 1 Punched‐out ulcer surrounded by cribriform scar on the anterior midline of the neck At surgical exploration, a thyroglossal duct tract was identified and a Sistrunk procedure was performed. This involved the removal of the thyroglossal duct cyst and the central portion of the hyoid bone, and the tracing of the thyroglossal duct tract to the foramen cecum at the base of the tongue. The pathology of the thyroglossal mass showed a thyroglossal duct cyst lined by columnar epithelium and small acini, with solid groups of large polyhedrial or round cells with pleomorphic hyperchromatic nuclei and eosinophilic granular cytoplasm, consistent with Hürthle cell adenoma ( Figs 2 and 3). No evidence of capsular invasion or penetration was observed. The patient was discharged in a good condition 1 week later, and was well at follow‐up 6 months later. 2 Hürthle cell adenoma (right) and thyroglossal duct cyst lined by columnar epithelium (left) are seen on the photomicrograph of the resected specimen (hematoxylin and eosin stain;×50) 3 High‐power photomicrograph of the Hürthle cell adenoma showing polyhedrial or round cells with abundant eosinophilic granular cytoplasm and pleomorphic hyperchromatic eccentric nuclei (hematoxylin and eosin stain;×400)

show abstract

Hürthle cell adenoma arising in a thyroglossal duct cyst

Cited by 10 publications

References 14 publications

Follicular adenoma in a thyroglossal duct

Follicular adenoma in a thyroglossal duct

Thyroglossal duct remnants

Hürthle cell adenoma of the thyroglossal duct fistula

Contact Info

Product

Resources

About