Abstract:Background: Diabetic cardiomyopathy (DCM) is a serious health-threatening diabetic complication characterized by myocardial fibrosis and abnormal cardiac function. Human umbilical cord mesenchymal stromal cells (hUC-MSCs) are considered as a potential therapeutic tool for DCM and myocardial fibrosis via the regulation of microRNA (miRNA) expression. This study aimed to investigate the therapeutic effects of tail vein injection of hUC-MSCs on DCM and determine effects on miRNA and target mRNA expression.
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