2023
DOI: 10.20944/preprints202312.0722.v1
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Human Tooth Developmental Anomaly: Odontoblastic Differentiation in Hamartomatous Calcifying Hyperplastic Dental Follicles Presenting DSP, Nestin, and HES1

Hiromasa Hasegawa,
Katsumitsu Shimada,
Takanaga Ochiai
et al.

Abstract: Hyperplastic dental follicles (HDFs) represent odontogenic hamartomatous lesions originating from pericoronal tissues and are often associated with impacted or embedded teeth. These lesions may occasionally feature unique calcifying bodies, known as calcifying whorled nodules (CWN), characterized by stromal cells arranged in a whorled or spiral fashion. CWNs are typically observed in multiple calcifying hyperplastic dental follicles or regional odontodysplasia. In our study, we examined 40 cases of HDFs, inclu… Show more

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