Human T-Cell Lymphotropic Virus Type I Association with
            <i>Strongyloı̈des stercoralis</i>
            : a Case Control Study among Caribbean Blood Donors from Guadeloupe (French West Indies)

Courouble, G.; Raffi, François; Herrmann-Storck, Cécile; Nicolas, Muriel; Candolfi, Ermanno; Strobel, M; Carme, Bernard

doi:10.1128/jcm.38.10.3903-3904.2000

Cited by 10 publications

(12 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Childhood infective dermatitis is associated with a high HTLV-1 PVL and with childhood bronchiectasis in Jamaica [ 34 ]. Although an association between HTLV-1 infection and Strongyloides seropositivity has not been consistently shown [ 35 , 36 ], the risk of symptomatic strongyloidiasis is increased among subjects with high HTLV-1 PVL [ 37 ]. The clinical markers of HTLV-1-associated bronchiectasis described here are therefore those HTLV-1-related diseases that are associated with high HTLV-1 PVL in other populations.…”

Section: Discussionmentioning

confidence: 99%

Higher Human T-Lymphotropic Virus Type 1 Subtype C Proviral Loads Are Associated With Bronchiectasis in Indigenous Australians: Results of a Case-Control Study

Einsiedel

Cassar

Goeman

et al. 2014

Open Forum Infectious Diseases

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Higher Human T-Lymphotropic Virus Type 1 Subtype C Proviral Loads Are Associated With Bronchiectasis in Indigenous Australians: Results of a Case-Control Study

Einsiedel

Cassar

Goeman

et al. 2014

Open Forum Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…Seven studies examined the prevalence of HTLV-1 and Strongyloides stercoralis co-infection: two from Australia ( 18 , 19 ), one from French West Indies ( 20 ), two from Brazil ( 21 , 22 ), two from Jamaica ( 23 , 24 ). Both studies from Brazil used stool examination for the diagnosis of S. stercoralis ( 21 , 22 ).…”

Section: Resultsmentioning

confidence: 99%

“…Both studies from Brazil used stool examination for the diagnosis of S. stercoralis ( 21 , 22 ). Serological examination was used in four studies ( 18 – 20 , 24 ) and one study from Jamaica used both types of examination ( 23 ) ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

Human T-Cell Lymphotropic Virus Type 1 and Strongyloides stercoralis Co-infection: A Systematic Review and Meta-Analysis

Taylor

Rosadas

2022

Front. Med.

View full text Add to dashboard Cite

BackgroundThe distribution of human T cell lymphotropic virus type 1 (HTLV-1) overlaps with that of Strongyloides stercoralis. Strongyloides stercoralis infection has been reported to be impacted by co-infection with HTLV-1. Disseminated strongyloidiasis and hyperinfection syndrome, which are commonly fatal, are observed in HTLV-1 co-infected patients. Reduced efficacy of anti-strongyloidiasis treatment in HTLV-1 carriers has been reported. The aim of this meta-analysis and systematic review is to better understand the association between HTLV-1 and S. stercoralis infection.MethodsPubMed, Embase, MEDLINE, Global Health, Healthcare Management Information Consortium databases were searched. Studies regarding the prevalence of S. stercoralis, those evaluating the frequency of mild or severe strongyloidiasis, and treatment response in people living with and without HTLV-1 infection were included. Data were extracted and odds ratios were calculated. Random-effect meta-analysis was used to assess the pooled OR and 95% confidence intervals.ResultsFourteen studies were included after full-text reviewing of which seven described the prevalence of S. stercoralis and HTLV-1. The odds of S. stercoralis infection were higher in HTLV-1 carriers when compared with HTLV-1 seronegative subjects (OR 3.2 95%CI 1.7–6.2). A strong association was found between severe strongyloidiasis and HTLV-1 infection (OR 59.9, 95%CI 18.1–198). Co-infection with HTLV-1 was associated with a higher rate of strongyloidiasis treatment failure (OR 5.05, 95%CI 2.5–10.1).ConclusionStrongyloides stercoralis infection is more prevalent in people living with HTLV-1. Co-infected patients are more likely to develop severe presentation and to fail treatment. Screening for HTLV-1 and Strongyloides sp. should be routine when either is diagnosed.

show abstract

“…2 However, this association remains controversial. 13 Conversely, it has been suggested that S. stercoralis might be a cofactor in the pathogenesis of HTLV-I-induced T cell lymphomas. 2,14 As observed in our patient before treatment, the lack of eosinophilia is typical in patients infected with HTLV-1 infection; this retrovirus enhances the production of interferon-␥, and decreases the production of interleukin-5 and the IgE response.…”

Section: Discussionmentioning

confidence: 99%

Subcutaneous Ivermectin as a Safe Salvage Therapy in Strongyloides Stercoralis Hyperinfection Syndrome: A Case Report

Pacanowski

Santos²,

Roux³

et al. 2005

The American Journal of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Strongyloides stercoralis hyperinfection syndrome due to the acceleration of the autoinfective cycle of the nematode is a life-threatening form of the infection occurring in immunocompromised hosts. Intestinal ileus, which is commonly encountered in this form, may reduce the bioavailability and thus the efficacy of oral anthelminthic drugs used in the treatment of the S. stercoralis hyperinfection syndrome. We report the efficacy and safety of subcutaneous administration of ivermectin in a patient infected with human T cell lymphotropic virus type I with S. stercoralis hyperinfection syndrome who was unresponsive to an oral combination of ivermectin and albendazole.

show abstract

Human T-Cell Lymphotropic Virus Type I Association with Strongyloı̈des stercoralis : a Case Control Study among Caribbean Blood Donors from Guadeloupe (French West Indies)

Cited by 10 publications

References 9 publications

Higher Human T-Lymphotropic Virus Type 1 Subtype C Proviral Loads Are Associated With Bronchiectasis in Indigenous Australians: Results of a Case-Control Study

Higher Human T-Lymphotropic Virus Type 1 Subtype C Proviral Loads Are Associated With Bronchiectasis in Indigenous Australians: Results of a Case-Control Study

Human T-Cell Lymphotropic Virus Type 1 and Strongyloides stercoralis Co-infection: A Systematic Review and Meta-Analysis

Subcutaneous Ivermectin as a Safe Salvage Therapy in Strongyloides Stercoralis Hyperinfection Syndrome: A Case Report

Contact Info

Product

Resources

About