Human Secretory Immunoglobulins

Brandtzæg, Per; Fjellanger, Ivar; Gjeruldsen, Sven T.

doi:10.1111/j.1600-0609.1970.tb01956.x

Cited by 157 publications

(1 citation statement)

References 240 publications

(252 reference statements)

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“…Also in table 1, 2 there was a significant increase at (P<0.001) in the mean serum and salivary IgA between different groups of diabetic patients (before and after treatment) and with the control. This finding is in agreement with the previous study by [25] , that showed the severity of periodontitis could be positively corleated with increased IgA concentrations, and there was a significant association between the diabetes mellitus and severe periodontal disease [26], and also the inaccuracy of estimating salivary IgA concentration is enhanced by loss of immunoglobulins during the process of concentration and by the adhesiveness of IgA to surface , and this will be in contrast with that found by [27], who showed that the fluid in gingival sulcus contained the same amount of IgG, IgA and IgM globulins as was found in their sera, but IgG and IgA were greatly decreased and IgM was absent in whole saliva The results in table -3 showed that the lysozyme concentration in serum of different groups of diabetic patients(before treatment) were not significant when compared with the control , whereas the lysozyme concentration in different groups of diabetic patients (after treatment) showed highly significant at (P<0.001) when compared with the control, and the best results of lysozyme concentration by the application of mixture of these plants (T5) . Also the results in table -4 showed that there was an elevation of whole unstimulated saliva lysozyme levels in NIDDM patients when compared with the controls.…”

Section: Fig( 3 )supporting

confidence: 93%

Effect of Some Medicinal Plants on the Activity of Some Immunological Factors in Saliva and Serum of Type –?? Diabetics

Al-Jammas,

Al-Mahdawi,

Al-Mukhtar

2014

Baghdad Sci.J

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The study involved 45 male and 45 females of diabetic patients type- ?? aged from 40-69years , and with the same numbers of males and females for control , all the patients and controls were without any periodontal diseases and without any systemic disease. Diabetic patients were divided in to three groups according to the degree of periodontitis , and the inflamed gingiva of all groups of diabetic patients were treated with the dried fruits powder (crude) of medicinal plants Quercus robur , Thuja occidenalis , Terminalia chebula, Anethum graveolens , respectively and mixture. Some immunological and antimicrobial factors (IgA, Lactoferrin , Lysozyme ) , were detected in serum and saliva of diabetic patients and the controls , the results revealed that the level of IgA , Lysozyme in saliva were more than in serum of the control , and this will insure that these factors are considered to be generally protected against bacteria in the oral cavity . Also there was a significant increase at (p?0.001) especially after treatment with the mixture of medicinal plants , so that the mixture of these plants can be considered the best type in the treatment of inflamed gingiva of type –?? diabetic patients.

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confidence: 93%