Human rotavirus genotypes in hospitalized children, South Korea, April 2005 to March 2007

Full genomic analysis of a human rotavirus G1P[8] strain isolated in South Korea

“…In South Korea, data from 1980 to 1999 showed that rotavirus accounted for 46% of 4,668 Korean children admitted to hospital with gastroenteritis [Seo and Sim, 2000]. However, data since 2003 has shown lower rotavirus‐positive rates of 19% (1,367/7,060) for 2003–2005 from Gyeonggi province hospitals [Huh et al, 2009], 18% (571/3,174) for 2004–2005 from Seoul metropolitan hospitals [Lee et al, 2008], and 22% (1,337/6,057) for 2005–2007 from eight major hospitals in Nationwide [Lee et al, 2009]. It is probably the improvement of income levels, and thought might be related to improved sanitation.…”

“…According to the Korea Centers for Disease Control & Prevention, most of the recent cases of gastroenteritis in South Korea were attributable to rotaviruses [http://www.cdc.go.kr/kcdchome/jsp/home/common/brd/COMMBRD0200List.jsp?menuid=101953&contentid=null&boardid=1550&appid=&pageNum=1&sub=5&sub2=1&tabinx=1&q_had01=A&q_had02=2011&loadType=null&s_year=2011&s_month=2&boardseq=null]. Data from 2005 to 2007 showed that the G1P[8] genotype accounted for 36% of 1,299 Korean children admitted to hospital with gastroenteritis [Lee et al, 2009]. However, the full genome analysis of the rotavirus G1P[8] strain has not been reported in South Korea.…”

Projecting the effectiveness of RotaTeq® against rotavirus-related hospitalizations and deaths in six Asian countries

“…18 In south Korea, samples were collected and tested (1-step RT-pcR) from 8 hospitals located in 3 metropolitan areas and 4 provincial regions from april 2005 to March 2007. 19 In Taiwan, samples were collected from 3 sentinel hospitals in northern, central, and southern Taiwan and testing (1-step real-time RT-pcR) was conducted at the centers for Disease control and prevention in Taiwan from January 2005 to December 2007. 19 In Thailand, samples were collected from 6 general hospitals located throughout Thailand and tested (2- …”

“…Therefore, these data, which are now >6 years RGE-related hospitalizations for each of the 6 Asian counties is shown in Table 1. [16][17][18][19][20][21] We estimated the projected effectiveness of RV5 by country to range between 70% and 94%.…”

“…Published surveillance data collected from 2006 to 2007 in China, 16 20 and from 2001 to 2003 in Thailand 21 provided the proportions of rotavirus serotypes attributable to G1, G2, G3, G4, G9 and G12 in children <5 years of age for each of the 6 Asian countries included in this model ( Table 4). [16][17][18][19][20][21] Published results from REST provided the baseline efficacy data of RV5 against RGErelated hospitalizations and emergency department (ED) visits for serotypes G1 (95%), G2 (88%), G3 (93%), G4 (89%), G9 (100%) and G12 (100%).…”