“…The P2X 7 R is predominantly expressed on cells of hematopoietic origin such as monocytes [24], dendritic cells, T and B lymphocytes, eosinophils, mast cells, but also on various types of glia within the peripheral and central nervous system including microglia, astrocytes, oligodendrocytes, and Schwann cells [25,26]. Moreover, P2X 7 R protein is expressed on epithelial cells, osteoblasts, synoviocytes, and fibroblasts [27][28][29][30].…”