2007
DOI: 10.1016/j.joen.2006.07.022
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Human Pulp Cells Response to Portland Cement In Vitro

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Cited by 91 publications
(96 citation statements)
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“…13 This has resulted in a signifi cant body of research showing that PC appears to be a useful substitute for MTA. 17,21,24,27,31,32 However, only four studies reported the use of PC in conservative pulp therapy with considerable success in rats 24 and dogs. 16,17,23 To the best of our knowledge, this is the fi rst randomised controlled clinical trial assessing the effectiveness of PC in human primary teeth and comparing this regenerative dressing agent with MTA.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…13 This has resulted in a signifi cant body of research showing that PC appears to be a useful substitute for MTA. 17,21,24,27,31,32 However, only four studies reported the use of PC in conservative pulp therapy with considerable success in rats 24 and dogs. 16,17,23 To the best of our knowledge, this is the fi rst randomised controlled clinical trial assessing the effectiveness of PC in human primary teeth and comparing this regenerative dressing agent with MTA.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, both MTA and PC allowed for dentin bridge formation after pulpotomy performed on dogs. 16 Min et al 27 observed that PC allowed the expression of mRNAs of a dentin-specifi c protein and a noncollagenous protein involved in mineralisation in cultured human pulp cells. De-Deus et al 28 presented a case in which substantial periapical healing occurred with the use of PC to create an apical plug in the root of an immature tooth in human.…”
Section: Introductionmentioning
confidence: 99%
“…The study also demonstrated that besides lowering the resistance to compression, the addition of bismuth oxide adversely affects the physical properties of MTA, contraindicating its use as a sealant in root perforations, especially in cases where high-resistance materials are recommend, such as furcation perforations. Studies comparing the biological properties of MTA and Portland cements have used Portland cements without additives 13,16 . Additives may improve the mechanical resistance of the cement, but also damage periradicular tissues.…”
Section: Discussionmentioning
confidence: 99%
“…Ordinary (type I) and white Portland cements have been compared with MTA in recent experimental studies on pulp capping in dogs 13 rat submucosal connective tissue 14 repair of root perforation of dog premolar teeth 15 and rat subcutaneous connective tissue 16 . Results obtained in these studies support the idea that both ordinary and white Portland cements have the potential to be used in clinical applications similar to those of MTA because of their physical, chemical and biological properties.…”
Section: Introductionmentioning
confidence: 99%
“…The cytotoxic effect of freshly mixed CGPC was also attributed to the high acidity of the freshly mixed cement (pH 1.6-3.7) when compared to that (pH 5.4-7.3) of the completely set cement [112]. The antimicrobial properties of CGPCs have been investigated in vitro and in vivo [113][114][115][116][117][118][119][120]. It was found that freshly mixed CGPCs inhibited bacterial growth, whereas completely set cement samples revealed no antimicrobial effect.…”
Section: Biocompatibilitymentioning
confidence: 99%