Human Pulmonary Infection by the Zoonotic Metastrongylus salmi Nematode. The First Reported Case in the Americas

Calvopiña, Manuel; Caballero, Henry; Morita, Tatsushi; Korenaga, Masaaki

doi:10.4269/ajtmh.16-0247

Cited by 18 publications

(17 citation statements)

References 4 publications

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“…Wild boars can harbour several Metastrongylus species, including M. asymmetricus, M. confusus , M. elongatus , M. apri , M. pudendotectus and M. salmi [ 55 – 57 ]. Of these, M. elongatus and M. salmi have been identified in humans as well as wild boars [ 41 , 58 ]. Metastrongylids were not identified to species level, and it is therefore unknown if zoonotic species were present.…”

Section: Discussionmentioning

confidence: 99%

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Surveillance of important bacterial and parasitic infections in Danish wild boars (Sus scrofa)

et al. 2020

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Background: Similar to the situation in other European countries, Danish wild boars may harbour a wide range of pathogens infectious to humans and domestic pigs. Although wild boars must be kept behind fences in Denmark, hunting and consumption of the meat may cause zoonotic transmission. Moreover, most infections of wild boars are transmissible to domestic pigs, which may have important economic consequences. The aim of this study was to investigate whether Danish wild boars were infected with bacteria and parasites transmissible to humans or domestic pigs: Brucella suis, methicillin-resistant Staphylococcus aureus (MRSA), Salmonella spp., Trichinella spp., lungworms and gastrointestinal parasites, especially Ascaris suum. This is the first study to investigate the prevalence of these important pathogens in Danish wild boars. Results: Wild boars from eight enclosures were analysed over a 5-year period. All tested wild boars were negative for B. suis (n = 240), MRSA (n = 244), Salmonella spp. (n = 115) and Trichinella spp. (n = 232), while eight parasite genera were identified in the faeces (n = 254): Ascaris suum, Capillaria sp., Cystoisospora suis, Eimeria spp., Metastrongylus sp. (lungworm), Strongyloides ransomi, Trichuris suis and strongylid eggs, i.e. strongyles not identified to the genera. Eimeria spp. and Metastrongylus sp. had the highest prevalence (92.3 and 79.5%, respectively) and were identified in wild boars from all eight enclosures, while the remaining parasite genera were present more sporadically. Conclusions: Wild boars from Denmark constitute a low risk of transmitting B. suis, MRSA, Salmonella spp. and Trichinella spp. to humans or domestic pigs, while economically important parasites transmissible to domestic pigs are highly prevalent in the wild boar population.

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Section: Discussionmentioning

confidence: 99%

“…Hence, parasitic infections may cause significant economic losses to the pig production. Additionally, the helminths A. suum and Metastrongylus are zoonotic [ 39 – 41 ] and the same may be true for Trichuris suis [ 35 ]. In humans, A. suum infection may cause severe visceral larval migrans causing liver and lung lesions [ 42 ].…”

Section: Introductionmentioning

confidence: 99%

Surveillance of important bacterial and parasitic infections in Danish wild boars (Sus scrofa)

et al. 2020

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“…While Metastrongylus sp. are known to occasionally infect other species including humans (Calvopina et al, 2016), the genus is generally thought to be specific to pigs. We also note that the genotype from dog 45 closely resembles that of a reptile-infecting Strongyloides sp.…”

Section: Discussionmentioning

confidence: 99%

Detection of classic and cryptic Strongyloides genotypes by deep amplicon sequencing: A preliminary survey of dog and human specimens collected from remote Australian communities

Beknazarova

Barratt

Bradbury

et al. 2019

Preprint

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17Strongyloidiasis is a neglected disease caused by the human infective nematodes 18 Strongyloides stercoralis, Strongyloides fuelleborni subsp. fuelleborni and Strongyloides 19 fuelleborni subsp. kellyi. The zoonotic potential of S. stercoralis and the potential role of dogs 20 in the maintenance of strongyloidiasis transmission has been a topic of interest and discussion 21 for many years. In Australia, strongyloidiasis is prevalent in remote socioeconomically 22 disadvantaged communities in the north of the continent. Being an isolated continent that has 23 been separated from other regions for a long geological period, knowledge on the diversity of 24 Australian Strongyloides genotypes is an important addition to our understanding of the genetic 25 diversity within the genus. Using PCR enrichment combined with Illumina sequencing 26 technology, we sequenced the Strongyloides SSU 18S rDNA hyper-variable I and hyper-27 variable IV regions using Strongyloides-specific primers, and a fragment of the mtDNA cox128 gene using primers that are broadly specific for Strongyloides sp. and hookworms. These loci 29 were amplified from DNA extracted from human and dog faeces, and one human sputum 30 sample. Using this approach, we confirm for the first time that potentially zoonotic S.

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“…although rare has been reported in the literature (Miloshev, 1956;Beaver et al, 1984;Calvopina et al, 2016).…”

Section: Nematodes Of Genusmentioning

confidence: 95%

Cystic echinococcosis and other helminth infections of wild boar in northeastern and northwestern regions of Tunisia

et al. 2019

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This study identified helminth species of wild boar (Sus scrofa) originating from northeastern and northwestern regions of Tunisia using 297 lungs, 297 livers, 264 intestinal tracts, 120 samples of muscle tissue (tongue, masseter, diaphragm, inter-costal) and 232 faecal samples derived from a total of 591 animals. Host gender was registered for the lung and liver wild boar group, which included 163 males and 134 females. All animals, excluding those used to retrieve muscular samples, were classified into three age classes, <2 (n = 212), 2–3 (n = 208) and ⩾4 years old (n = 141). Helminth fauna of the examined wild boar included 14 parasite species: one trematode (adult, Brachylaemus suis), three cestodes (metacestodes of Echinococcus granulosus, Taenia hydatigena cysticercus, adult, Hymenolepis diminuta), nine nematodes (adults of Metastrongylus apri, Metastrongylus pudendotectus, Ascarops strongylina, Globocephalus urosubulatus, Physocephalus sexalatus, Gnathostoma hispidum, Gongylonema pulchrum and eggs of Strongyloides ransoni and Capillaria spp.) and one acanthocephalan (adult, Macracanthorhynchus hirudinaceus). Trichinella larvae were not recovered from any of the 30 wild boar examined. Results showed a 73.5% global prevalence of infection with visceral helminths, 67.3% of which were lung and hepatic infections and 80.3% of helminths were recovered from the gastrointestinal tract. The most prevalent parasite was M. hirudinaceus (61.7%) while the highest intensity of infection was observed for Metastrongylus spp. The most prevalent cestode was E. granulosus (18.9%). This is the first detailed study on helminth infections of wild boar from a North African country.

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Human Pulmonary Infection by the Zoonotic Metastrongylus salmi Nematode. The First Reported Case in the Americas

Cited by 18 publications

References 4 publications

Surveillance of important bacterial and parasitic infections in Danish wild boars (Sus scrofa)

Surveillance of important bacterial and parasitic infections in Danish wild boars (Sus scrofa)

Detection of classic and cryptic Strongyloides genotypes by deep amplicon sequencing: A preliminary survey of dog and human specimens collected from remote Australian communities

Cystic echinococcosis and other helminth infections of wild boar in northeastern and northwestern regions of Tunisia

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