Human prefrontal cortex: processing and representational perspectives

Wood, Jacqueline N.; Grafman, Jordan

doi:10.1038/nrn1033

Cited by 594 publications

(426 citation statements)

References 98 publications

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“…This is consistent with the idea put forward by Grafman and colleagues that the mPFC is especially tuned towards the integration of relevant stimuli over time [Huey et al, 2006;Krueger et al, 2007;Wood and Grafman, 2003;Wood et al, 2005]. In the social domain, this takes the form of traits and scripts of social behavior.…”

Section: Summary and Discussionsupporting

confidence: 90%

“…However, of the many brain functions explored, only sequence learning seems to be tied intimately to social cognition, as both areas of activation overlap entirely. This provides support for the idea that the mPFC is crucially involved in the integration of information across time, be it social or not (Huey et al, 2006;Krueger et al, 2007;Wood and Grafman, 2003;Wood et al, 2005). This meta-analysis also documented a substantial overlap with emotional and reward processing, which confirms the long-held idea that the mPFC is strongly involved in the integration of different sort of information.…”

Section: Enduring Traits and Scriptssupporting

confidence: 77%

“…Alternatively, recent neurological evidence suggests that neurons in the mPFC are uniquely oriented to time and fire over extended periods of time and across events [Huey et al, 2006;Wood and Grafman, 2003]. This has led to the hypothesis that the mPFC serves the integration of social information over time, by storing this information in r Social Cognition and Brain r r 833 r traits or scripts [Huey et al, 2006].…”

Section: How the Mpfc Identifies Social Beliefs Traits And Scriptsmentioning

confidence: 99%

“…Response Sequence: It has been hypothesized that enduring social inferences and knowledge on traits and scripts require the integration of chronological sequences over larger time intervals, and that this time integration is performed in the mPFC [Huey et al, 2006;Wood and Grafman, 2003]. This implies that the mPFC is engaged in several form of sequence learning, not only in social script learning.…”

Section: Is Social Cognition Subserved By Other Brain Functions?mentioning

confidence: 99%

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Social cognition and the brain: A meta‐analysis

Overwalle

2008

Human Brain Mapping

1,527

102

1,300

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This meta-analysis explores the location and function of brain areas involved in social cognition, or the capacity to understand people's behavioral intentions, social beliefs, and personality traits. On the basis of over 200 fMRI studies, it tests alternative theoretical proposals that attempt to explain how several brain areas process information relevant for social cognition. The results suggest that inferring temporary states such as goals, intentions, and desires of other people-even when they are false and unjust from our own perspective-strongly engages the temporo-parietal junction (TPJ). Inferring more enduring dispositions of others and the self, or interpersonal norms and scripts, engages the medial prefrontal cortex (mPFC), although temporal states can also activate the mPFC. Other candidate tasks reflecting general-purpose brain processes that may potentially subserve social cognition are briefly reviewed, such as sequence learning, causality detection, emotion processing, and executive functioning (action monitoring, attention, dual task monitoring, episodic memory retrieval), but none of them overlaps uniquely with the regions activated during social cognition. Hence, it appears that social cognition particularly engages the TPJ and mPFC regions. The available evidence is consistent with the role of a TPJ-related mirror system for inferring temporary goals and intentions at a relatively perceptual level of representation, and the mPFC as a module that integrates social information across time and allows reflection and representation of traits and norms, and presumably also of intentionality, at a more abstract cognitive level.

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Section: Summary and Discussionsupporting

confidence: 90%

Section: Enduring Traits and Scriptssupporting

confidence: 77%

Section: How the Mpfc Identifies Social Beliefs Traits And Scriptsmentioning

confidence: 99%

Section: Is Social Cognition Subserved By Other Brain Functions?mentioning

confidence: 99%

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Social cognition and the brain: A meta‐analysis

Overwalle

2008

Human Brain Mapping

1,527

102

1,300

View full text Add to dashboard Cite

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“…The frontal lobe, especially the prefrontal cortex (PFC) plays an essential role in various high‐level cognitive functions, such as executive functions (Mansouri, Tanaka, & Buckley, 2009; Miller, 2000; Miller & Cohen, 2001), reasoning and planning (Wood & Grafman, 2003), decision making (Wallis, 2007), social cognition, and moral judgment (Forbes & Grafman, 2010). Meanwhile, the deficits in PFC functions are involved in the pathophysiology of several psychiatric and neurological disorders such as schizophrenia, drug addiction, mood disorders, and Alzheimer's disease (Fuster, 2001; Goto, Yang, & Otani, 2010).…”

Section: Introductionmentioning

confidence: 99%

Neuroticism and conscientiousness respectively positively and negatively correlated with the network characteristic path length in dorsal lateral prefrontal cortex: A resting‐state fNIRS study

Wang

Zhang

et al. 2018

Brain and Behavior

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BackgroundAccumulating evidence shows that the dorsal lateral prefrontal cortex (dlPFC) is implicated in personality traits. In this study, resting‐state functional near infrared spectroscopy (fNIRS) combined with small‐world analysis was utilized to examine the relationship between the network properties of dlPFC and personality traits.MethodsThirty college students (aged between 20 and 29) were recruited from the University of Macau campus, whose personality scores were accessed with the NEO‐FFT questionnaire. Graph theory combined with resting‐state fNIRS data was used to quantify the network properties of dlPFC, whereas Pearson correlation analysis was performed to generate the relationship between the small‐world indicators and personality scores.ResultsCompared to matched random networks, the resting‐state brain networks exhibited a larger clustering coefficient (C p, 0.1–0.66), shorter characteristic path length (L p, 0.1–0.66), and higher global (E g, 0.1–0.66) and local efficiency (E loc, 0.1–0.65). In particular, conscientiousness (r = −0.63) and neuroticism (r = 0.40) respectively showed negative and positive correlation with the L p.ConclusionsThe resting‐state functional brain networks in dlPFC exhibited the small‐world properties. In addition, participants with higher conscientiousness scores showed a shorter L p.

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Cognitive Neuroscience of Thinking

Goel

2009

Handbook of Neuroscience for the Behavioral Sciences

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Human prefrontal cortex: processing and representational perspectives

Cited by 594 publications

References 98 publications

Social cognition and the brain: A meta‐analysis

Social cognition and the brain: A meta‐analysis

Neuroticism and conscientiousness respectively positively and negatively correlated with the network characteristic path length in dorsal lateral prefrontal cortex: A resting‐state fNIRS study

Cognitive Neuroscience of Thinking

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