Abstract:Human pluripotent stem cells (hPSCs) can give rise to a vast array of
differentiated derivatives, which have gained great attention in the field of
in vitro
toxicity evaluation. We have previously
demonstrated that hPSC-derived alveolar epithelial cells (AECs) are
phenotypically and functionally similar to primary AECs and could be more
biologically relevant alternatives for assessing the potential toxic materials
including in fine dust and cigarette smoking. Therefore, in this study, we… Show more
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