“…Beta2-glycoprotein I (Agar et al, 2011), also known under the name of Apolipoprotein H (ApoH) is one of the acute phase proteins exhibiting the most striking scavenger properties, strikingly is able to catch early apoptotic cells in a Ca2+-independent manner(d 'Angeac et al, 2005). This protein traps every kind of pathogenic microorganisms, including parasites (examples: Leishmania donovani, Plasmodium falciparum, etc), Gram + or Gram -bacteria (Escherichia coli, Salmonella, Listeria monocytogenes, Staphylococcus aureus, etc) and RNA or DNA enveloped or non-enveloped viruses (Hepatitis B, Hantaviruses, HIV, Rotaviruses, and others viruses) (Godoy et al, 2009;Stefas et al, 1997;Stefas et al, 2001). In addition, products of the complement pathways, in turn, promote inflammation; chemoattract phagocytes to the infected zone, also attach microbes to phagocytes, and finally induce cytolysis of infected cells.…”