Human Parvovirus-Associated Arthritis: A Clinical and Laboratory Description

Clinical and epidemiological aspects of human parvovirus B19 infection in an urban area in Brazil (Niterói city area, State of Rio de Janeiro, Brazil)

“…Frequently, the disease was characterized by variable combinations of rash, flu-like symptoms and arthropathy. As described in the literature (Reid et al 1985), less than 10% of the children had arthralgias or joint swelling, these complaints being substantially higher in adults (62.5%), particularly female adults. The arthropathy was symmetrical, affecting more often small joints of hands, feet, knees, wrists.…”

“…Adults, particularly females, with erythema infectiosum, frequently present joint symptoms (Reid et al 1985). Parvovirus B19 also causes transient aplastic crisis in patients with underlying hemolytic anemia (Pattison et al 1981), persistent anemia in immunocompromised patients (Kurtzman et al 1989) and hydrops fetalis and fetal loss during pregnancy (Brown et al 1984).…”

Human parvovirus B19 infection and hydrops fetalis in Rio de Janeiro, Brazil

“…In adults, particularly women, the rash illness is less frequent, but there may be involvement of joints leading to acute arthritis (Reid et al 1985). In addition, B19 is also a major cause of aplastic crisis in patients suffering from hemolytic anemias (Pattison et al 1981).…”

Virale Arthritiden und Vaskulitiden

“…Es wird vermutet, dass die Arthritis eine immunvermittelte Genese hat, da sie mit dem Auftreten zirkulierender Antikörper im Serum zusammenfällt. Die Gelenksymptome manifestieren sich als akute moderate bis schwere, nichterosive Polyarthritis mit Beteiligung der Metakarpophalangealgelenke (75 %), Kniegelenke, Hand-und Sprunggelenke sowie einer signifikanten Morgensteifigkeit [17].…”