Human parvovirus arthropathy

Dougados, Maxime; Lefrère, J.‐J.; Couroucé, A. M.

doi:10.1002/art.1780290422

Cited by 6 publications

(1 citation statement)

References 5 publications

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“…Arthropathy following B19V infection was described soon after the virus was linked to fifth disease (450,451). In patients with serological confirmation of infection, many will have recently experienced a rash (450)(451)(452)(453)(454)(455)(456)(457). Arthritis-swelling and redness-as well as pain mimic rheumatoid arthritis in joint distribution, but in most cases, resolution occurs within a few weeks of symptoms and signs (451), and upon long-term follow-up, patients are without symptoms (458).…”

Section: Clinical Manifestations Diseases Caused By B19v Infectionmentioning

confidence: 99%

Human Parvoviruses

2017

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Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large Parvoviridae family, are human pathogens responsible for a variety of diseases. For B19V in particular, host features determine disease manifestations. These viruses are prevalent worldwide and are culturable in vitro, and serological and molecular assays are available but require careful interpretation of results. Additional human parvoviruses, including HBoV2 to -4, human parvovirus 4 (PARV4), and human bufavirus (BuV) are also reviewed. The full spectrum of parvovirus disease in humans has yet to be established. Candidate recombinant B19V vaccines have been developed but may not be commercially feasible. We review relevant features of the molecular and cellular biology of these viruses, and the human immune response that they elicit, which have allowed a deep understanding of pathophysiology.

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