Human papova (wart) virus.

Abstract

Wart on finger Wart on hand Warts on back and arms Wart on hand Warts on hand Condylomata Warts on head Warts on hand Warts on neck Warts on hand Condylomata Fresh warts Glycerine-preserved warts Normal skin Filtrate-induced warts Laryngeal warts Filtrate-induced warts Filtrate-induced warts Condylomata Suprapubic wart Skin warts Laryngeal warts Warts on hand Condylomata Warts on face N.

Viral “Tumorigenesis” in man: Cell markers in condylomata acuminata

“…Each condyloma acuminatum is a large cauliflowerlike bunch of many verrucous subunits, several of which are organized into clusters which themselves are components of larger units. The responsible agent, a papova virus, is the only virus which has been proven to be tumorigenic in man (reviewed by Rowson and Mahy, 1967). Our data not only indicate that even the small individual verrucous subunits have multiple cell origin, but also provide information concerning the manner in which condylomata acitminata develop.…”

“…The "venereal " wart, like the common wart, is caused by a papova virus (reviewed by Rowson and Mahy, 1967), but in contrast to the double enzyme phenotypes found in the former, Muhay and associates (1971) reported single enzyme phenotypes in six common warts from as many G-6-PD heterozygotes. Assuming that the common and "venereal " wart papova viruses are the same, the finding that the former tumors may have a unicellular origin, while the latter have a multicellular origin, suggests a significant effect of local environmental conditions such, for example, as may affect ease of viral spread) or the size of the initial innoculum on the pattern of tumorigenesis.…”

Pulsed Dye Laser Treatment is Effective in the Treatment of Recalcitrant Viral Warts

“…Treatment using local agents has a remission rate of approximately 56% to 80% but these results mostly apply to simple warts. 5,[7][8][9][10][11][12] Imiquimod has been found to be a topical immune response modifier agent that inhibits angiogenesis and is used to treat a broad range of angiogenesisdependent dermatologic conditions, including actinic keratosis and basal cell carcinoma and external genital warts. Despite the good results in treating genital warts, only 30% of recalcitrant cutaneous warts responded to imiquimod.…”

“…It is a common problem affecting approximately 10% of the population. 1,2 Warts often cause pain and may interfere with function. These complications, cosmetic embarrassment, and the risk of spreading to other areas of skin are indications for treatment, 3 which can be a challenge.…”

“…Cure rates are described in literature for simple warts as being between 56 and 80% for common therapies, including salicylic acid, cryotherapy, 5-fluorouracil, and carbon dioxide laser therapy. [5][6][7][8][9][10][11][12] We have shown in a study that the cure rate of carbon dioxide laser reaches 77%, but recidivism is high at a rate of 22.6%. 13 Warts that fail to respond to conventional treatment are considered to be recalcitrant.…”