Human Papillomavirus Types 2, 27, and 57 Identified in Plantar Verrucae from HIV-Positive and HIV-Negative Individuals

Abstract

This study presents an increased prevalence of HPV-2, HPV-27, and HPV-57 in plantar verrucae in this study population and provides insight into the occurrence of these types in HIV+ and HIV- individuals.

Detection of Human Papillomavirus among Patients with Clinically Diagnosed Cutaneous Warts by PCR Method

“…FAP primer pair-based method is a suitable option, because this method allows detection of 65 HPV subtypes with high sensitivity in a clinical setting, even the quantity of collected DNA is low. This method was originally introduced by Forslund in 1999 and has been successfully applied in many HPV typing studies [7], among a number of other primer sets used in clinical and epidemiology studies to detect HPV prevalence in verruca and healthy skin samples [9][10][11][12][13][14][15]. To our knowledge, this is the first study to evaluate HPV infection encompassing so many HPV types on a large cohort with cutaneous warts.…”

Plantar Warts: Epidemiology, Pathophysiology, and Clinical Management

“…Species are categorized into 1 of 5 genera, including α, β, γ, m, and ν. 11,15,16 The species of HPV can also be broadly categorized according to whether they preferentially cause cutaneous or mucosal lesions or both. 8,16 The types of HPV that have been isolated from plantar warts include HPV-1, -2, -3, -4, -27, -29, -57, -60, -63, -65, -66, and -69.…”

“…8,16 The types of HPV that have been isolated from plantar warts include HPV-1, -2, -3, -4, -27, -29, -57, -60, -63, -65, -66, and -69. 15,17,18 In one randomized controlled trial, 88% of plantar warts were caused by HPV-1, -2, -27, or -57.3 18 Most plantar warts are attributed to HPV-1, however. 19 While most plantar wart-causing HPV types belong to the categories of cutaneous or mucosal/cutaneous lesions, there are rare instances, such as in immunocompromised persons, in which a mucosal HPV type can cause cutaneous lesions, including plantar warts.…”

Human papillomavirus type 2 associated with pyogenic granuloma in patients without clinical evidence of warts

“…It is well recognized that cutaneous warts are caused by HPV infection . The following HPV types are frequently detected in cutaneous warts: types 2, 7, 27, and 57 from the alpha genus; types 4 and 65 from the gamma genus; and type 1 from the mu genus …”

“…2,12 The following HPV types are frequently detected in cutaneous warts: types 2, 7, 27, and 57 from the alpha genus; types 4 and 65 from the gamma genus; and type 1 from the mu genus. 9,[13][14][15][16] In this study, we assessed the presence of HPV DNA in pyogenic granuloma samples. Notably, HPV-2 was the only HPV type present in the eight HPV DNA-positive samples.…”