Human Papillomavirus

Polymerase chain reaction analysis of the surgical margins of equine sarcoids for bovine papilloma virus DNA

“…Virus latency is well known for papilloma viruses. The presence of viral DNA in circulating lymphocytes in cattle has been confirmed, and human papilloma virus DNA associated with cervical cancer has been found in a high number of asymptomatic individuals 33,34 . Except for one study, 35 there has been no evidence for the latent presence of BPV DNA, either in lymphocytes of sarcoid‐affected horses, or in samples from apparently normal skin in horses with and without sarcoids 10,11,14,36 .…”

Hybrid capture vs. PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 1270 women

“…It is known that development of precancerous lesions may shortly follow infection with HPV, despite the belief that long-term infection is a prerequisite for such an event [34]. Thus, these women should be prospectively followed by their gynecologist and submitted to cytology and other testing, as appropriate[35,36]. The use of HPV testing has been recommended for women with ASCUS[37] and it has been shown that approximately one third of women with HSIL are subsequently identified from an initial ASCUS diagnosis [25].…”

Inverse relationship between the expression of the human papillomavirus type 16 transcription factor E2 and virus DNA copy number during the progression of cervical intraepithelial neoplasia

“…While most HPV-associated lesions will remain benign or will regress spontaneously, approximately 15% of all HPV-positive cases will progress to high-grade cervical intraepithelial neoplasia (CIN) (Fowler, 1993 ; DiSaia & Creasman, 1989 ) and cancers, which almost invariably contain DNA of high-risk HPV types, e.g. HPV-16 (zur Hausen, 1994 ; Richart et al , 1998 ).…”