Human otoacariasis caused by Amblyomma testudinarium

Nakao, Yoshio; Tanigawa, Tohru; Shibata, Rei

doi:10.1097/md.0000000000007394

Cited by 11 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…and Dermacentor spp. were associated with human otoacariasis, especially Amblyomma testudinarium (8) and Dermacentor steini (9). However, Haemaphysalis spp.…”

Section: Introductionmentioning

confidence: 99%

The Bacterial Community in Questing Ticks From Khao Yai National Park in Thailand

et al. 2021

View full text Add to dashboard Cite

Ticks are known vectors for a variety of pathogens including bacteria, viruses, fungi, and parasites. In this study, bacterial communities were investigated in active life stages of three tick genera (Haemaphysalis, Dermacentor, and Amblyomma) collected from Khao Yai National Park in Thailand. Four hundred and thirty-three questing ticks were selected for pathogen detection individually using real-time PCR assays, and 58 of these were subjected to further metagenomics analysis. A total of 62 ticks were found to be infected with pathogenic bacteria, for a 14.3% prevalence rate, with Amblyomma spp. exhibiting the highest infection rate (20.5%), followed by Haemaphysalis spp. (14.5%) and Dermacentor spp. (8.6%). Rickettsia spp. were the most prevalent bacteria (7.9%) found, followed by Ehrlichia spp. (3.2%), and Anaplasma spp. and Borrelia spp. each with a similar prevalence of 1.6%. Co-infection between pathogenic bacteria was only detected in three Haemaphysalis females, and all co-infections were between Rickettsia spp. and Anaplasmataceae (Ehrlichia spp. or Anaplasma spp.), accounting for 4.6% of infected ticks or 0.7% of all examined questing ticks. The prevalence of the Coxiella-like endosymbiont was also investigated. Of ticks tested, 65.8% were positive for the Coxiella-like endosymbiont, with the highest infection rate in nymphs (86.7%), followed by females (83.4%). Among tick genera, Haemaphysalis exhibited the highest prevalence of infection with the Coxiella-like endosymbiont. Ticks harboring the Coxiella-like endosymbiont were more likely to be infected with Ehrlichia spp. or Rickettsia spp. than those without, with statistical significance for Ehrlichia spp. infection in particular (p-values = 0.003 and 0.917 for Ehrlichia spp. and Rickettsia spp., respectively). Profiling the bacterial community in ticks using metagenomics revealed distinct, predominant bacterial taxa in tick genera. Alpha and beta diversities analyses showed that the bacterial community diversity and composition in Haemaphysalis spp. was significantly different from Amblyomma spp. However, when examining bacterial diversity among tick life stages (larva, nymph, and adult) in Haemaphysalis spp., no significant difference among life stages was detected. These results provide valuable information on the bacterial community composition and co-infection rates in questing ticks in Thailand, with implications for animal and human health.

show abstract

“…and Dermacentor spp. were associated with human otoacariasis, especially Amblyomma testudinarium (8) and Dermacentor steini (9). However, Haemaphysalis spp.…”

Section: Introductionmentioning

confidence: 99%

The Bacterial Community in Questing Ticks From Khao Yai National Park in Thailand

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Though the aural infestation of a tick may not be an emergency, it needs to be addressed due to the pain, inflammation and local irritation that it will lead to. 9 Studies done on otoacariasis such as that by Indhudaran et al have described complications spanning from ear bleeding, vertigo to even facial nerve weakness with otitis media. 10 Ticks are known to release neurotoxins which inhibit acetylcholine, thus leading to respiratory distress or even paralysis.…”

Section: Discussionmentioning

confidence: 99%

A nasty guest of EAC - A rare case report of human otoacariasis

Vasudevan¹,

Belaldavar

Apoorva³

2022

IJOAS

View full text Add to dashboard Cite

Otalgia has a spectrum of causes and one among them is a foreign body in the EAC. Insects are not uncommon, but pose a threat by virtue of carrying infections that affect the patient locally as well as systemically.A 42-year female patient presented with acute onset otalgia, examination by otoendoscopy showed a foreign body over the posterior superior canal wall and it was removed, further microscopy then diagnosed it as Ambylomma Testudinarium and patient was treated accordingly.In tropical and developing countries such as India otologists must be aware and watchful of EAC infestations by arthropod vectors. Farmers are more prone to this zoonotic infection. Ticks consume a blood meal and hatch eggs, causing local irritation, perforations and hematogenic spread of infection.Tick infestations though rare are perilous due to the risk of tick-borne infections, which have grave complications. The management must be holistic including the otological perspective with systemic treatment.

show abstract

“…Recently, a novel thogotovirus, named as Oz virus, was isolated from A. testudinarium collected in Ehime prefecture, Japan (Ejiri et al, 2018). Cases of human bites have been reported elsewhere (Isohisa et al, 2011;Nakao et al, 2017). Moreover, the cases of tickassociated rash illness (TARI) showing manifestation of erythema migrans (EM) without association of Lyme disease have been reported in the patients who were bitten by this tick species (Natsuaki et al, 2014).…”

mentioning

confidence: 99%

Comparative mitogenomics elucidates the population genetic structure of Amblyomma testudinarium in Japan and a closely related Amblyomma species in Myanmar

Mohamed

Moustafa

Thu

et al. 2022

Evolutionary Applications

View full text Add to dashboard Cite

Ticks are the second most important vector capable of transmitting diseases affecting the health of both humans and animals. Amblyomma testudinarium Koch 1844 (Acari: Ixodidae), is a hard tick species having a wide geographic distribution in Asia.In this study, we analyzed the composition of A. testudinarium whole mitogenomes from various geographical regions in Japan and investigated the population structure, demographic patterns, and phylogeographic relationship with other ixodid species. In addition, we characterized a potentially novel tick species closely related to A. testudinarium from Myanmar. Phylogeographic inference and evolutionary dynamics based on the 15 mitochondrial coding genes supported that A. testudinarium population in Japan is resolved into a star-like haplogroup and suggested a distinct population structure of A. testudinarium from Amami island in Kyushu region. Correlation analysis using Mantel test statistics showed that no significant correlation was observed between | INTRODUC TI ONTicks are obligatory ectoparasites that feed on the blood of various vertebrate species including mammals, birds, and reptiles (Brites-Neto et al., 2015). There are three major tick families described, namely, Ixodidae, Argasidae, and Nuttalliellidae (Horak et al., 2002). Some species of Ixodidae (hard ticks) and Argasidae (soft ticks) are implicated in the transmission of several bacterial, viral, and protozoan pathogens to humans and animals. Ticks are widely distributed around the world, especially in warm humid regions to remain hydrated and subsequently undergo metamorphosis (Vail & Smith, 1998).Amblyomma is the third biggest genus of Ixodidae ticks with more than 130 species (Guglielmone et al., 2014), some of which act as disease vectors of many pathogens, for instance Rickettsia tamurae and Rickettsia raoultii causing spotted fever (Fournier et al., 2006;Piotrowski & Rymaszewska, 2020), Ehrlichia chaffeensis causing ehrlichiosis (Cao et al., 2000), and severe fever with thrombocytopenia syndrome (SFTS) virus causing SFTS in humans (Suh et al., 2016). The geographical distribution of Amblyomma species is expanding due to anthropogenic activities, climate change, and increased geographical ranges of animal hosts (Childs & Paddock, 2003). In the United States, Amblyomma americanum populations have been constantly enlarging that contributed to change in the epidemiology of spotted fever group rickettsiosis in the country (Dahlgren et al., 2016;Sagurova et al., 2019). In Africa, Amblyomma species transmit Ehrlichia ruminantium and Rickettsia africae that cause heartwater disease and African tick-bite fever in animals and humans, respectively (Kelly et al., 1996;Yunker, 1996). Furthermore, although very little is known about the diseases caused by pathogens transmitted by this group of ticks (Jabin et al., 2019), there are 14 Amblyomma species in Asia (Voltzit, 2002), and at least three species, including

show abstract

Human otoacariasis caused by Amblyomma testudinarium

Cited by 11 publications

References 11 publications

The Bacterial Community in Questing Ticks From Khao Yai National Park in Thailand

The Bacterial Community in Questing Ticks From Khao Yai National Park in Thailand

A nasty guest of EAC - A rare case report of human otoacariasis

Comparative mitogenomics elucidates the population genetic structure of Amblyomma testudinarium in Japan and a closely related Amblyomma species in Myanmar

Contact Info

Product

Resources

About