“…Neutrophils downregulate a number of membrane proteins as they age, including CD16 (FcγRIII), CD31 (PECAM-1), CD32, CD35 (Complement receptor 1), CD43, CD45, CD44, CD47 (IAP), CD50 (ICAM-3), CD55 (Complement regulatory protein DAF), CD62L (L-selectin), CD63, CD66b, CD87 (uPAR), CD88 (C5a receptor), and CD120a (tumor necrosis factor receptor 1), thus significantly changing the apoptotic neutrophil surface. [35][36][37][38][39][40] Some of these proteins, including CD31 and ICAM-3, are also functionally modified, 41,42 whereas other proteins, including ICAM-1, are upregulated on apoptotic neutrophils. [41][42][43] Finally, new antigens are expressed on the surface of apoptotic neu-…”