Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas
Márcia Quinhones P. Lopes,
Raquel Lima F. Teixeira,
Pedro Hernan Cabello
et al.
Abstract:Introduction: Several polymorphisms altering the NAT2 activity have already been identified. The geographical distribution of NAT2 variants has been extensively studied and has been demonstrated to vary significantly among different ethnic population. Here, we describe the genetic variability of human N-acetyltransferase 2 (NAT2) gene and the predominant genotype-deduced acetylation profiles of Brazilians.Methods: A total of 964 individuals, from five geographical different regions, were genotyped for NAT2 by … Show more
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