Human Metabolic Profiles Obtained by GC and GC/MS

Volatile organic compounds in seawater

“…This progress was motivated by the biomedical profession's desire to utilize metabolic profiles to assess patients' health (Horning and Horning, 1971;Zlatkis et al,.. 1973, Teranishi et aL., 1972 and the desire to monitor drinking waters and other natural freshwaters for volatile pollutants Novotny et aL., 1974;Dowty et aL., 1975;Bertsch et aL., 1975;Hites, 1977). These advances were primarily of twö kinds.…”

A Perceptive of Mass Spectrometry in Clinical Chemistry: Hyphenation for Benefit of Mankind

“…MS-based analysis in clinical chemistry has been carried out since 1970s, based on targeted methods focusing on particular metabolites or chemical families [13][14][15][16]. Toxicological screening is very common in clinical chemistry and it is involved with the metabolomics [17][18][19][20].…”

Symbiosis of chemometrics and metabolomics: past, present, and future

“…This history is very well documented by Gates et al [21] and illustrates how quantitative metabolic profiling evolved, and the term metabolic profile was suggested. In this review, also the work of Horning was emphasized as introducing in 1971 the metabolic profile terminology [22].…”