Human Meniscus Transplantation

Er, van Arkel; Hh, de Boer

doi:10.1007/978-3-0348-7442-7_29

Cited by 7 publications

(10 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some biomechanical studies have addressed the function of meniscal grafts [1, 2, 8, 36], and found that suturing them without firm bony fixation of the anterior and posterior horns failed to restore contact pressures to normal, leading to contact mechanics similar to those after meniscectomy. Despite these findings, the early [6, 10, 12, 33, 46, 47, 52] and longer‐term [50, 53] clinical results of meniscal transplantation using simple suturing have been encouraging. In contrast to the earlier studies, the present experiments did lead to restoration of joint contact pressures that did not differ significantly from normal, with suture fixation alone, although that was an advantage for the grafts with bone fixation.…”

Section: Discussionmentioning

confidence: 99%

The effects of lateral meniscal allograft transplantation techniques on tibio-femoral contact pressures

McDermott

Lie

Edwards

et al. 2008

Knee Surg Sports Traumatol Arthr

112

View full text Add to dashboard Cite

This paper reviews and updates our knowledge of the anatomy and biomechanics of the posterior cruciate ligament, and of the posterolateral, posteromedial and meniscofemoral ligaments of the knee. The posterior cruciate ligament is shown to have two functional fibre bundles that are tight at different angles of knee flexion. It is the primary restraint to tibial posterior draw at all angles of knee flexion apart from near full extension. In contrast, the posterolateral and posteromedial structures are shown to tighten as the knee extends, and to be well-aligned to resist tibial posterior draw. These structures also act as primary restraints against other tibial displacements. Tibial internal rotation is restrained by the medial and posteromedial structures, while tibial external rotation is restrained by the lateral and posterolateral structures. They are also the primary restraints against tibial abduction-adduction rotations. The meniscofemoral ligaments are shown, for the first time, to contribute significantly to resisting tibial posterior draw, and to have a strength of approximately 300 N. Taken together, this evidence shows how the posterolateral and posteromedial structures are responsible for posterior knee stability near extension, and this, along with the action of the meniscofemoral ligaments, may explain why an isolated rupture of the posterior cruciate ligament does not often lead to knee instability

show abstract

Section: Discussionmentioning

confidence: 99%

The effects of lateral meniscal allograft transplantation techniques on tibio-femoral contact pressures

McDermott

Lie

Edwards

et al. 2008

Knee Surg Sports Traumatol Arthr

112

View full text Add to dashboard Cite

show abstract

“…9,18 Favorable long-term survival results of MAT have been reported, 6,9,22,30,31 and MAT has become a treatment option for symptomatic meniscus-deficient knees. 8,24,28,32 In the early era of MAT surgery, despite the use of different endpoints to define failure, results were not satisfactory, with failure rates of up to 47%. 19 In recent studies, however, investigators report more favorable long-term outcomes (85%-90% success rates) by avoiding previously known risk factors of graft failure (advanced degree of arthrosis, untreated lower limb malalignment, and uncorrected knee joint instability).…”

mentioning

confidence: 99%

Nonanatomic Horn Position Increases Risk of Early Graft Failures After Lateral Meniscal Allograft Transplantation

Kim¹,

Bin

Lee

et al. 2018

Am J Sports Med

View full text Add to dashboard Cite

Background: The cause of early graft failure within 1 year of meniscal allograft transplantation (MAT) remains unclear. The association of early failure with a nonanatomic horn position of the allograft after lateral MAT with the keyhole technique has never been evaluated. Hypothesis: A nonanatomic horn position of an allograft would be a significant risk factor for a premature graft tear as compared with an anatomically positioned allograft. Study Design: Cohort study; Level of evidence, 3. Methods: From October 2007 to October 2016, 208 patients (214 knees) with primary isolated lateral MAT in a single center were enrolled. A >5-mm or 10% discrepancy between pre- and postoperative horn position was defined as “nonanatomic,” and the early failure rate was compared. Among 214 cases of lateral MAT, 54 were nonanatomically positioned, and 160 were anatomically positioned. The early failures (within 1 year after MAT) were defined as (1) grade 3 signal intensities (tears) over one-third of the allograft on magnetic resonance image or (2) removal of more than one-third of the allograft because of tears. Results: Among the early failure cases, 6 were in the nonanatomic group and 5 in the anatomic group. The failure rate was 11.1% (6 of 54) in the nonanatomic group and 3.1% (5 of 160) in the anatomic group, with a 5.1% (11 of 214) overall early failure rate. The nonanatomic horn position group had an increased risk of early graft failure as compared with the anatomically positioned group (odds ratio = 3.88; 95% CI, 1.13-13.26). Anteriorized and lateralized horn position was identified in the nonanatomic group as compared with the anatomic group. Differences in patient age, sex, body mass index, involved knee, cartilage status, alignment of lower extremity, and joint space width were not statistically significant between the groups. Conclusion: Horn position discrepancy was associated with an increased risk of early graft failures. Meticulous insertion of a bone bridge is needed to ensure anatomically correct horn positioning to avoid early graft failure in lateral MAT with the keyhole technique.

show abstract

“…67 Cellular repopulation was restored after three months of cryopreservation and approached a normal level after one year in both groups. Despite protection of chondrocytes by cryopreservation of menisci in 10% DMSO, cartilage cells underwent damage, especially at the level of intermediate cartilage.…”

Section: Cryopreservation Of Cartilagementioning

confidence: 89%