1994
DOI: 10.1016/0009-9120(94)90011-6
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Human liver plasma membranes contain an enzyme activity that removes membrane anchor from alkaline phosphatase and converts it to a plasma-like form

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Cited by 27 publications
(5 citation statements)
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“…It plays an important role in osteoid formation and mineralization by enzymatic degradation of the inhibitor of mineralization, pyrophosphate at an alkaline pH. [12] ALP is the first BTM to be used in both clinical and research setting. Several isoforms of ALP have been identified in liver, intestine, placenta, and bone.…”
Section: Serum Alkaline Phosphatase (Total and Bone-specific Alkalinementioning
confidence: 99%
“…It plays an important role in osteoid formation and mineralization by enzymatic degradation of the inhibitor of mineralization, pyrophosphate at an alkaline pH. [12] ALP is the first BTM to be used in both clinical and research setting. Several isoforms of ALP have been identified in liver, intestine, placenta, and bone.…”
Section: Serum Alkaline Phosphatase (Total and Bone-specific Alkalinementioning
confidence: 99%
“…Following glabridin supplementation, they were decreased when compared with DM rats. SAKP is a membrane bound enzyme glycoprotein enzyme (27). Expression of this enzyme is increased when the bile ducts become blocked.…”
Section: Discussionmentioning
confidence: 99%
“…Alkaline phosphatase ( ALP ) is a serological marker directly related to skeletal development and, in particular, to bone formation and growth ( Seibel, 2005 ). ALP is a ubiquitous enzyme attached on the outer cell surface ( Stinson and Hamilton, 1994 ); the precise function of the enzyme is still unknown, but it obviously plays an important role in osteoid formation and mineralization ( Harris, 1990 ). This serological marker is now an important tool in the assessment and differential diagnosis of metabolic bone diseases in humans; nevertheless, it has never been used in broiler breeder pullets to assess body development during the rearing period.…”
Section: Introductionmentioning
confidence: 99%