Human Leukocyte Antigen Alleles and Haplotypes Associated with Selective Immunoglobulin A Deficiency in Spanish Pediatric Patients
Nora Clerici,
Miguel Fernández,
Isabel Saiz
et al.
Abstract:SummaryClass I and II human leukocyte antigens were determined by a standard microlymphocytotoxity test in a group of 45 pediatric patients with selective immuno‐globulin A deficiency (IgA‐D), 33 of them with frequent respiratory tract infections, allergic diseases, or gastrointestinal disorders (RTIAG), and 12 with celiac disease (CD). The results showed that the DR1 allele, and the A1,B8,Cw7,DR3,DQw2; B35,Cw4,DR1,DQw1; and B14,DR1,DQw1 haplotypes could be involved with IgA‐D susceptibility in RTIAG patients.… Show more
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