Human isolates of Staphylococcus caprae: association with bone and joint infections

Shuttleworth, R; Behme, R. J.; McNabb, A.; Colby, W. David

doi:10.1128/jcm.35.10.2537-2541.1997

Cited by 46 publications

(32 citation statements)

References 18 publications

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“…This cross-hybridization of the SEP-1 gene probe with S. capitis, S. saccharolyticus, and S. caprae has also been described recently by Zakrzewska-Czerwinska et al (34). S. capitis, S. saccharolyticus, and S. caprae have been shown to have a certain pathogenic potential (e.g., S. caprae can be associated with bone and joint infections in humans [20,32]), but clearly, they are rarely isolated human pathogens (1, 22), whereas the vast majority of this type of infections are caused by S. epidermidis. Therefore, it is unlikely that the cross-reactivity of the SEP-1 probe will pose a real problem, particularly as the treatment strategy would be the same as that for an S. epidermidis infection.…”

Section: Resultssupporting

confidence: 72%

Detection of Staphylococcus aureus and Staphylococcus epidermidis in Clinical Samples by 16S rRNA-Directed In Situ Hybridization

et al. 1999

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Staphylococcus epidermidis and Staphylococcus aureus are the most common causes of medical device-associated infections, including septicemic loosenings of orthopedic implants. Frequently, the microbiological diagnosis of these infections remains ambiguous, since at least some staphylococci have the capacity to reduce their growth rate considerably. These strains exhibit a small-colony phenotype, and often they are not detectable by conventional microbiological techniques. Moreover, clinical isolates ofS. aureus and S. epidermidis adhere to polymer and metal surfaces by the generation of thick, multilayered biofilms consisting of bacteria and extracellular polysaccharides. This study reports improved detection and identification of S. aureusand S. epidermidis by an in situ hybridization method with fluorescence-labeled oligonucleotide probes specific for staphylococcal 16S rRNA. The technique has proven to be suitable for the in situ detection of staphylococci, which is illustrated by the identification of S. epidermidis in a connective tissue sample obtained from a patient with septicemic loosening of a hip arthroplasty. We also show that this technique allows the detection of intracellularly persisting bacteria, including small-colony variants of S. aureus, and the differentiation of S. epidermidisfrom other clinically relevant staphylococci even when they are embedded in biofilms. These results suggest that the 16S rRNA in situ hybridization technique could represent a powerful diagnostic tool for the detection and differentiation of many other fastidious microorganisms.

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Section: Resultssupporting

confidence: 72%

Detection of Staphylococcus aureus and Staphylococcus epidermidis in Clinical Samples by 16S rRNA-Directed In Situ Hybridization

et al. 1999

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“…found that isolates of Staph. caprae from udders of uninfected goats express potential virulence factors (different exoproteins and slime) ; other researchers have occasionally isolated it from clinical cases of goat mastitis (Deinhofer & Pernthaner, 1995), or from human clinical specimens associated with bone and joint infection (Vandenesh et al 1995 ;Shuttleworth et al 1997). In spite of these forms of pathogenicity, some studies have not shown significant increases in somatic cell count (SCC) of milk from goat udder halves infected by Staph.…”

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confidence: 99%

Effect of intramammary infection by Staphylococcus caprae on somatic cell counts and milk composition in goats

Sánchez

Fernández

Contreras

et al. 2002

Journal of Dairy Research

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Since its identification by Devirese et al. (1983), Staphylococcus caprae has been frequently isolated from udder halves of goats with subclinical intramammary infection (IMI) (Contreras et al. 1995; Poutrel et al. 1996). Several different studies have demonstrated the capacity of Staph. caprae to persist throughout lactation (Poutrel et al. 1996; Contreras et al. 1997; Bedidi-Madani et al. 1998a) and during the dry period (Poutrel, 1984). Bedidi-Madani et al. (1998a) found that isolates of Staph. caprae from udders of uninfected goats express potential virulence factors (different exoproteins and slime); other researchers have occasionally isolated it from clinical cases of goat mastitis (Deinhofer & Pernthaner, 1995), or from human clinical specimens associated with bone and joint infection (Vandenesh et al. 1995; Shuttleworth et al. 1997). In spite of these forms of pathogenicity, some studies have not shown significant increases in somatic cell count (SCC) of milk from goat udder halves infected by Staph. caprae (Deinhofer & Pernthaner, 1995; Poutrel et al. 1996). Moreover, there is a lack of information on the effect of infection by this mammary pathogen on milk yield and composition. Knowledge of repercussions for hygiene and production would be useful in mastitis control programmes in view of the high frequency of isolation (higher than 22% of the staphylococci isolated) of Staph. caprae in dairy goat herds (Contreras et al. 1995; Poutrel et al. 1996). The aim of the present investigation was to ascertain the significance of persistent subclinical IMI by Staph. caprae on SCC, milk yield and physical-chemical parameters of Murciano-Granadina goat milk at mid-lactation.

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“…El microorganismo aislado en los hemocultivos y bazo fue S. caprae. Es una bacteria grampositiva, coagulasa negativa, agente poco frecuente como causante de EI, y generalmente asociada a infección ósea, especialmente si hay material protésico (9) . Los casos no asociados a infecciones óseas son muy infrecuentes.…”

Section: Discusión Diagnósticounclassified

Endocarditis infecciosa a Staphylococcus caprae con múltiples embolias preoperatorias graves y vegetación mitral gigante residual

2019

Rev. Urug. Cardiol.

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Endocarditis infecciosa a Staphylococcus caprae con múltiples embolias preoperatorias graves y vegetación mitral gigante residual ResumenLa endocarditis infecciosa (EI) es una enfermedad infrecuente, heterogénea en su presentación, con una alta mortalidad global y frecuente indicación de cirugía cardíaca. Presentamos el caso de una joven con EI a S. caprae y múltiples embolias preoperatorias graves. Dado que se presenta al ingreso con infección en curso, absceso esplénico y vegetación remanente de muy alto riesgo embólico, plantea un dilema terapéutico en cuanto a oportunidad quirúrgica y orden en que deben resolverse las complicaciones de su enfermedad infecciosa. En este caso se procedió a cirugía vascular, posteriormente esplenectomía y por último cirugía valvular, todas en breve plazo, logrando resolver la patología integralmente y sin complicaciones. Palabras clave: ENDOCARDITIS BACTERIANA STAPHYLOCOCCUS CAPRAE ABSCESO Infectious endocarditis to Staphylococcus caprae with multiple severe preoperative embolisms and residual giant mitral vegetation SummaryInfective endocarditis is an infrequent disease, heterogeneous presentation, with high mortality, and frequent indication of heart surgery. We introduce the case of a young woman, with S. caprae infective endocarditis, and multiple preoperative serious emboli. Since she presents at admission with infection in progress, splenic abscess and mitral vegetation with high embolic risk, it poses a therapeutic dilemma regarding surgical opportunity and the order in which the complications should be resolved. In this case we proceeded to vascular surgery, then splenectomy and finally valve surgery, all in a short time, to solve the pathology integrally and without complications. Endocardite infecciosa para Staphylococcus caprae com múltiplos embolismos pré-operatórios severos e vegetação mitral gigante residual ResumoA endocardite infecciosa é uma doença infrequente, de apresentação heterogênea, com alta mortalidade e frequente indicação de cirurgia cardíaca. Apresentamos o caso de uma jovem mulher com endocardite infecciosa a S. caprae e múltiplos êmbolos pré-operatórios graves. Por se apresentar na admissão com infecção em curso, abscesso esplênico e vegetação mitral com alto risco embólico, apresenta um dilema terapêutico em relação à oportunidade cirúrgica e a ordem em que as complicações devem ser resolvidas. Neste caso precedeu à cirurgia vascular, depois à esplenectomia e finalmente à cirurgia valvar, tudo em um curto espaço de tempo, para resolver integralmente a patologia e sem complicações. Revista Uruguaya de Cardiología Carta científica Volumen 34 | nº 2 | Julio 2019 Carta científica Revista Uruguaya de Cardiología Volumen 34 | nº 2 | Julio 2019 Figura 2. Vegetación mitral gigante y friable. Vista auricular. Ocupa toda el orificio mitral y gran parte de la aurícula izquierda. Múltiples lóbulos. La válvula mitral se encuentra completamente oculta por la vegetación. Revista Uruguaya de Cardiología Carta científica Volumen 34 | nº 2 | Julio 2019 211 Figura 3....

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Human isolates of Staphylococcus caprae: association with bone and joint infections

Cited by 46 publications

References 18 publications

Detection of Staphylococcus aureus and Staphylococcus epidermidis in Clinical Samples by 16S rRNA-Directed In Situ Hybridization

Detection of Staphylococcus aureus and Staphylococcus epidermidis in Clinical Samples by 16S rRNA-Directed In Situ Hybridization

Effect of intramammary infection by Staphylococcus caprae on somatic cell counts and milk composition in goats

Endocarditis infecciosa a Staphylococcus caprae con múltiples embolias preoperatorias graves y vegetación mitral gigante residual

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