“…Equal numbers of male and female mice were employed. All animals were housed in the Animal Resource Center at the Case Western Reserve University School of Medicine (Cleveland, (continued from previous page) 13-hydroxy-9Z,11E-octadecadienoic acid; 15-HETE, 15-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid; AA, arachidonic acid; AAd8, arachidonic acid with 8 deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions; AMD, age-related macular degeneration; ARMS2, age-related maculopathy susceptibility 2; DHA, docosahexaenoic acid; DHA-d5, docosahexaenoic acid with 5 deuterium atoms at the 21, 21, 22, 22, and 22 positions; EPA, eicosapentaenoic acid; EPA-d5, eicosapentaenoic acid with 5 deuterium atoms at the 19,199,20,20, and 20 positions; F2 isoprostane, 9a,11a,15R-trihydroxy-(8b)-prosta-5Z,13E-dien-1-oic acid; FA, formic acid; LA, linoleic acid; MS/MS, tandem mass spectrometry; m/z, mass to charge ratio; ONL, outer nuclear layer; OR, odds ratio; PA, palmitic acid; ROC, receiver operator characteristic; SIM, selected ion monitoring; SD-OCT, spectral domain-optical coherence tomography OH, USA), where they were maintained in complete darkness. …”