Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome

Abstract

Larry Chi-Kin Yung, National Key Program for Infectious Diseases of China.

Mycophenolic acid, an immunomodulator, has potent and broad-spectrum in vitro antiviral activity against pandemic, seasonal and avian influenza viruses affecting humans

“…All virus strains used in this study were isolated from patients ( Table 1). The virus strains H1/415, H7/ AH1 and H7/ZJ1 were used in our previous studies (Chan et al, 2013b;Chen et al, 2013;Li et al, 2009;Zheng et al, 2008). These viruses were propagated in MDCK cells before use.…”

Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus

“…A single reoccurring case was just reported on 15 October, in Zhejiang Province, China. Until now, there have been no confirmed cases of human-to-human transmission, and most infected humans had a history of contact with poultry or of having visited a wet market [2][3][4][5][6] , although suspected human-to-human transmission has been described 7 . Our previous analyses on the first released virus genomes proposed that this virus might have emerged from at least four origins by means of genetic reassortment 3 .…”

Quantitative risk analysis of the novel H7N9 virus in environments associated with H9 avian influenza virus, Zhejiang province, China

“…The reported case numbers are still increasing [3]. Evidence supports the origination hypothesis of triple reassortment between H9N2 virus and H7 and N9 viruses [4][5][6][7].…”