“…The recombination breakpoint for non-segmented positive-strand RNA viruses, such as polioviruses and other picornaviruses (Santti et al, 1999;Guillot et al, 2000;Kew et al, 2002), as well as members of the family Flaviviridae, are often located in the part of the genome encoding the non-structural proteins but sometimes in genes encoding structural proteins (CostaMattioli et al, 2003;Martin et al, 2002). Moreover, several possible recombination breakpoints have been identified in other RNA viruses, such as human immunodeficiency virus (HIV), and many more are being reported (Onafuwa et al, 2003;Vidal et al, 2003;Strimmer et al, 2003;Najera et al, 2002). The recombination point in our recombinant strain was situated in the NS5B region (see Figs 2 and 3).…”