Human Herpesviruses in Hematologic Diseases

Csire, Márta; Mikala, Gábor

doi:10.5772/28490

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“…Current screening, however, excludes three common lymphotropic human herpesviruses (HHV), namely the Epstein–Barr virus (EBV), HHV‐6 and HHV‐7. Primary infection by these viruses can cause infectious mononucleosis, roseola and pityriasis rosea, respectively, after which viral DNA continues to reside latently in a small fraction of B lymphocytes . Moreover, these viruses can cause debilitating disease in immunocompromised patients and are highly prevalent among blood donors .…”

Section: Introductionmentioning

confidence: 99%

Detection of Epstein–Barr virus in leucoreduced blood products

Trottier

Delage

et al. 2015

Vox Sanguinis

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This study examined the prevalence of three human herpesviruses (HHV), namely HHV-4 (Epstein-Barr virus/EBV), HHV-6b and HHV-7 in leucoreduced blood products obtained from the Sainte-Justine Hospital blood bank. A total of 100 specimens, including 34 red blood cell concentrates, 33 platelet bags and 33 plasma units, were collected and screened by a sensitive PCR assay using virus-specific primers. Positive units were then retested by quantitative PCR. Of the 100 specimens, one platelet unit tested positive for EBV.

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Section: Introductionmentioning

confidence: 99%