Human Health Risk from Metals in Fish from Saudi Arabia: Consumption Patterns for Some Species Exceed Allowable Limits

Burger, Joanna; Gochfeld, Michael; Alikunhi, Nabeel M.; Al-Jahdali, Haitham; Al-Jebreen, Dalal Hamad; Al-Suwailem, Abdulaziz M.; Aziz, Mohammed A. M.; Batang, Zenon B.

doi:10.1080/10807039.2014.934585

Cited by 7 publications

(5 citation statements)

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“…Only two species induced a HQ > 1 [101] Malaysia HQ Between 1.5 and 2.7 for urban and coastal rural women of childbearing age, respectively [102] Jeddah, Saudi Arabia Only one of the 13 samples fish species exceeded the 0.5 mg kg -1 FS for mercury. Seven species had a HQ > 1 [103] that the bioavailable fraction of mercury from these piles is thought to be minimal. By contrast, more recent studies measuring mercury in North Sea seawater samples found concentrations around 0.5 ng l -1 [107], although others stated concentrations between 0.5 and 200 ng l -1 [108].…”

Section: Zhoushan Chinamentioning

confidence: 99%

An approach to assessing subsea pipeline-associated mercury release into the North Sea and its potential environmental and human health impact

von Hellfeld,

Hastings

2024

R. Soc. Open Sci.

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Mercury is a naturally occurring heavy metal that has also been associated with anthropogenic sources such as cement production or hydrocarbon extraction. Mercury is a contaminant of concern as it can have a significant negative impact on organismal health when ingested. In aquatic environments, it bioaccumulates up the foodweb, where it then has the potential to impact human health. With the offshore hydrocarbon platforms in the North Sea nearing decommissioning, they must be assessed as a potential source for the environmental release of mercury. International treaties govern the handling of materials placed in the ocean. Studies have assessed the ecologic and economic benefits of (partial) in situ abandonment of the infrastructure as artificial reefs. This can be applied to pipelines after substantial cleaning to remove mercury accumulation from the inner surface. This work outlines the application of an approach to modelling marine mercury bioaccumulation for decommissioning scenarios in the North Sea. Here, in situ decommissioning of cleaned pipelines was unlikely to have a negative impact on the North Sea food web or human health. However, significant knowledge gaps have been determined, which must be addressed before all negative impacts on ecosystems and organismal health can be excluded.

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Section: Zhoushan Chinamentioning

confidence: 99%

An approach to assessing subsea pipeline-associated mercury release into the North Sea and its potential environmental and human health impact

von Hellfeld,

Hastings

2024

R. Soc. Open Sci.

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“…Due to the bioaccumulation and bioconcentration process, the influence of heavy metals can be detected on land via the food web [ 11 ]. It is important to constantly monitor fish species for concentration of heavy metals as it provides a good indication of pollution status [ 12 ]. Contaminated fish is an important source of heavy metal exposure in humans.…”

Section: Introductionmentioning

confidence: 99%

Risk Assessment of Heavy Metals in Selected Marine Fish Species of Gadani Shipbreaking Area and Pakistan

Kakar

Hayat

Abbasi

et al. 2020

Animals

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Gadani shipbreaking area, located on the coastline of Pakistan, is an important fish production area. In this study, levels of four metals (Ni, Pb, Cd, and Mn) in 148 muscle and gill samples of seven fish species (Small-scale terapon, Torpedo scade, Sicklefish, Saddle grunt, Gold silk seabream, Indian mackerel, Spotted sickle fish) and seawater samples, taken from 9 sampling sites in the shipbreaking area, were determined. In addition, multiple approaches were used to assess human health risks from fish consumption. Trace metal concentration in seawater ranged from 0.05 to 1.96 mg/L in shipbreaking vicinity and 0.03 to 0.97 mg/L in the reference site (Miani Hor). However, metal accumulations in fish species ranged from 1.33 to 5.26 μg/g. Among trace metals, the level of Pb in all fish species was highest, followed by Ni, Mn, and Cd. The bioaccumulation factors (BAFs) for both gills and muscles displayed the order: Mn > Cd > Ni > Pb. Estimated daily intake (EDI) values were below the tolerable daily intake (TDI). Based on target hazard quotient (THQ), the investigated fish species were safe regarding Pb and Mn (THQ < 1), while they may cause potential risk regarding Cd and Ni (THQ > 1). After comparison with maximum permissible limits, heavy metal concentration in the edible muscle tissues of all the analyzed fish species from the Gadani coast were found safe for human consumption.

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“…Among the chemical forms of mercury, the major health concerns are related to the organic forms, i.e., methylmercury (MeHg + ). MeHg + is found in the aquatic environment as a product of Hg 2+ methylation by microorganisms [24], once formed MeHg + bioaccumulates in the food chain [25–28]. Consequently, the consumption of piscivorous fish by humans is of concern since they are a relevant source of MeHg + [20–22, 29, 30].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses

Piccoli

Segatto

Oliveira

et al. 2019

BMC Pharmacol Toxicol

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BackgroundExposure to vinylcyclohexene (VCH) and methylmercury (MeHg+) can induce oxidative stress and gene modulation. Several studies have been evaluating the effects of VCH and MeHg+, but little is known about interactive effects between them. This work aimed to assess the exposure and co-exposure effects of MeHg+ and VCH on oxidative stress and gene modulation in Drosophila melanogaster.MethodsReactive species production, glutathione S-transferase (GST) and acetylcholinesterase (AChE) activities were evaluated after exposure and co-exposure to VCH (1 mM) and MeHg+ (0.2 mM) for one or three days in the head and body (thorax and abdomen) of flies. The expression of genes related to redox state and inflammatory response was evaluated after exposure and co-exposure to VCH and MeHg+ for three days.ResultsSurvival decreased only in flies co-exposed to VCH and MeHg+ for three days. All treatments increased total reactive species production after one day of exposure. However, no significant changes were observed in the head after three days of exposure. One day of exposure to VCH caused an increase in the head GST activity, whereas MeHg+ induced an increase after three days of exposure. Regarding the body, all treatments increased GST activity after one day of exposure, but only the flies exposed to MeHg+ presented an increase in GST activity after three days of exposure. Treatments did not alter AChE activity in the head. As for gene expression, there was a significant increase in the Relish transcription factor gene in the flies’ body, but Nrf2, Keap1, Jafrac1, TrxR1, and NF-κβ were not altered.ConclusionThe results suggest that exposure to VCH and MeHg+ induce oxidative stress and activation of an inflammatory response in fruit flies.

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Human Health Risk from Metals in Fish from Saudi Arabia: Consumption Patterns for Some Species Exceed Allowable Limits

Cited by 7 publications

References 50 publications

An approach to assessing subsea pipeline-associated mercury release into the North Sea and its potential environmental and human health impact

An approach to assessing subsea pipeline-associated mercury release into the North Sea and its potential environmental and human health impact

Risk Assessment of Heavy Metals in Selected Marine Fish Species of Gadani Shipbreaking Area and Pakistan

Simultaneous exposure to vinylcyclohexene and methylmercury in Drosophila melanogaster: biochemical and molecular analyses

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