Human hand allograft: report on first 6 months

Dubernard, Jean‐Michel; Owen, Earl; Herzberg, Guillaume; Lanzettà, Marco; Martín, Xavier; Kapila, Hari; Dawahra, M; Hakim, Nadey

doi:10.1016/s0140-6736(99)02062-0

Cited by 639 publications

(290 citation statements)

References 24 publications

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“…CTA was however abandoned because of greater antigenicity of the skin. However, following significant strides in immunosuppression therapy by mid 1990s, the first successful CTA in modern history was accomplished with a hand transplant performed by a team of surgeons in Lyon, France under Jean-Michel Dubernard in September 1998 [55][56][57]. However, facial CTAs presented much more complex problems because of more pertinent ethical and psychological considerations.…”

Section: Facial Allotransplantationmentioning

confidence: 99%

Evolution and Trends in Reconstructive Facial Surgery: An Update

Akadiri

2012

J. Maxillofac. Oral Surg.

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Surgical correction of congenital and acquired facial deformities has transcended the primitive era of using non biologic materials to current attempts at own face growing through biotechnology. A summative account of this trend is still lacking in the literature. The objective of this article is to present an update on current knowledge in the strides to achieve functionally and aesthetically perfect facial reconstruction. It highlights the impact of advancements in 3D imaging, stereolithographic biomodelling, microvascular surgical tissue transplantation and tissue biotechnology in the surgical efforts to solve the problems of facial disfigurement whether congenital or acquired.

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Section: Facial Allotransplantationmentioning

confidence: 99%

Evolution and Trends in Reconstructive Facial Surgery: An Update

Akadiri

2012

J. Maxillofac. Oral Surg.

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“…(37) We assumed that a maintenance immunosuppressive medication regimen used a triple drug combination of tacrolimus (4-8 mg/day), mycophenolate mofetile (MMF) (2g/day) and prednisolone (10mg/day) based published series (1,7,10). Immunosuppressive medication may change with better understanding of the unique requirements of hand transplantation.…”

Section: Costsmentioning

confidence: 99%

An Economic Analysis of Hand Transplantation in the United States

Oda

Shauver

Chung

2009

The Journal of Hand Surgery

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“…The patients who were thought to fit the including criteria were seen on a regular basis (around once a month), given all the available information and updated on the progress of the patients who had the procedures carried out in France and the USA (37)(38)(39)(40).…”

Section: Staff Requisites and Organization Of The Clinical Trialmentioning

confidence: 99%

Hand Transplantation: The Milan Experience

Lanzettà¹,

Nolli²,

Vitale³

et al. 2007

Polish Journal of Surgery

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The authors describe the most critical aspects of transplantation of the hand. Three successful cases are presented from the Italian Hand Transplantation National Program. The key issues of this new type of surgical reconstruction for major amputations are selection criteria of suitable candidates, technical aspects of surgery, postoperative regime and functional rehabilitation. Other important aspects are staff requisites and organisation of the clinical trial, ethical and legal implications, dealing with the media. The authors comment on the fact that we might be ready to accept that almost anything could come from a cadaver, even if it is not a life-saving organ, to reconstruct missing parts and restore anatomical integrity and, especially, function.

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Human hand allograft: report on first 6 months

Cited by 639 publications

References 24 publications

Evolution and Trends in Reconstructive Facial Surgery: An Update

Evolution and Trends in Reconstructive Facial Surgery: An Update

An Economic Analysis of Hand Transplantation in the United States

Hand Transplantation: The Milan Experience

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