Abstract:There is growing evidence to suggest that severe disease in children infected with common viruses that are typically benign in other children can result from inborn errors of immunity or their phenocopies. Infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a cytolytic respiratory RNA virus, can lead to acute hypoxemic COVID‐19 pneumonia in children with inborn errors of type I interferon (IFN) immunity or autoantibodies against IFNs. These patients do not appear to be prone to severe … Show more
“…The concentration of inflammatory cells in the blood typically serves as an indicator of the host's overall infection status. 63 As illustrated in Fig. S16, † the postoperation levels of monocytes and neutrophils in rats for the Ti-SPD-Cl group are notably lower than those for the Ti group, suggesting that Ti-SPD-Cl effectively inhibits the systemic inflammatory response resulting from osteomyelitis.…”
Section: In Vivo Anti-infection Assessmentmentioning
Modified Ti with a porous N-halaminated spermidine-containing polymeric coating is constructed, and it has both excellent antibacterial and osteogenic abilities to enhance osseointegration, making it potentially applicable in orthopedics.
“…The concentration of inflammatory cells in the blood typically serves as an indicator of the host's overall infection status. 63 As illustrated in Fig. S16, † the postoperation levels of monocytes and neutrophils in rats for the Ti-SPD-Cl group are notably lower than those for the Ti group, suggesting that Ti-SPD-Cl effectively inhibits the systemic inflammatory response resulting from osteomyelitis.…”
Section: In Vivo Anti-infection Assessmentmentioning
Modified Ti with a porous N-halaminated spermidine-containing polymeric coating is constructed, and it has both excellent antibacterial and osteogenic abilities to enhance osseointegration, making it potentially applicable in orthopedics.
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