Human exposure to airborne pollen and relationships with symptoms and immune responses: Indoors versus outdoors, circadian patterns and meteorological effects in alpine and urban environments

Damialis, Athanasios; Häring, Franziska; Gökkaya, Mehmet; Rauer, Denise; Reiger, Matthias; Bezold, Sebastian; Bounas-Pyrros, Nikolaos; Eyerich, Kilian; Todorova, Antonia; Hammel, Gertrud; Gilles, Stefanie; Traidl‐Hoffmann, Claudia

doi:10.1016/j.scitotenv.2018.10.366

Cited by 49 publications

(40 citation statements)

References 49 publications

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“…Even though the exact relationship between symptoms (pulmonary, nasal or ocular) and pollen occurrence and abundance is not yet clear, there are some recent reports clarifying this interaction (e.g. Berger et al 2013;Bastl et al 2014;Karatzas et al 2014;Osborne et al 2017;Voukantsis et al 2015;Damialis et al 2019). Overall, there are indications that there is a positive correlation between allergic symptoms and pollen abundance.…”

Section: Allergenic Pollen and Epidemiologymentioning

confidence: 99%

Climate Change and Pollen Allergies

Damialis

Traidl‐Hoffmann

Treudler

2019

Biodiversity and Health in the Face of Climate Change

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This chapter reviews the emerging importance of pollen allergies in relation to ongoing climate change. Allergic diseases have been increasing in prevalence over the last decades, partly as the result of the impact of climate change. Increased sensitisation rates and more severe symptoms have been the partial outcome of: increased pollen production of wind-pollinated plants resulting in longterm increased abundance of pollen in the air we breathe; earlier shifts of airborne pollen seasons making occurrence of allergic symptoms harder to predict and deal with efficiently; increased allergenicity of pollen causing more severe health effects in allergic individuals; introduction of new, invasive allergenic plant species causing new sensitisations; environment-environment interactions, such as plants and hosted microorganisms, i.e. fungi and bacteria, which comprise a complex and dynamic system, with additive, presently unforeseeable influences on human health;

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Section: Allergenic Pollen and Epidemiologymentioning

confidence: 99%

Climate Change and Pollen Allergies

Damialis

Traidl‐Hoffmann

Treudler

2019

Biodiversity and Health in the Face of Climate Change

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“…2 Global warming is responsible for alarming changes, including increased total pollen amount, earlier shifts of pollen seasons with levels expected to be four times higher by 2050, invasion of allergenic plants with resultant increases in allergic sensitisation, and increased amounts of allergenic protein in pollen. 3 The changing environment, the major health ramifications and the biodiversity of South Africa underline a need for widespread pollen monitoring. In this paper, we follow Galán et al 4 in regard to aerobiological terminology.…”

Section: The Problemmentioning

confidence: 99%

Aerobiology in South Africa: A new hope!

et al. 2020

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Pollen and fungal spores (aerospora) are the major atmospheric bioaerosols. Aerospora occurrence and concentration vary by geographical region and blossoming period, and with meteorological factors. Allergic respiratory diseases affect about 20 million South Africans, with pollen and fungal allergens amongst the leading triggers. Asthma triggered by aerospora can be life threatening; allergic rhinitis causes considerable morbidity and carries financial implications for individuals and health systems. Thus, knowledge about geographical variation, seasonal timing and intensity, as well as annual aerospora fluctuations in South Africa, where climate and vegetation are exceptionally diverse, is essential for effective diagnosis and treatment of allergies. Unfortunately, there is a lack of continuous aeropalynological data from South Africa. The longest annual monitoring exists for Cape Town (~20 years), with almost no data out of the Cape since the 1990s, and many parts of South Africa have never been monitored. In this brief review, we highlight the cross-disciplinary need for strengthened and expanded continuous aeropalynological study in South Africa, the history of efforts to date, and the introduction of the interdisciplinary South African Pollen Network (SAPNET). SAPNET was launched in seven major cities in August 2019 in order to monitor weekly variations of aerospora, and provide online data for allergy sufferers and health-care providers (www.pollencount.co.za) with the aim to establish regional pollen calendars.

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“…Seventeen of the retained studies had a cross-sectional design (21%) [73][74][75][76][77][78][79][80][81][82][83][84][85][86][87][88][89], and twelve were experimental (15%) (i.e., three randomized trials on metabolomic profile alterations [90,91] or clinical health outcomes [92] following administration of the experimental exposure; two open label cross-over trials exploring metabolomic and clinical effects of an experimental (juice) [93,94] or environmental (airborne and grass pollen) intervention [95], and seven experimental non-randomized studies). Five studies were case-control (6%) [94,[96][97][98][99] and three case-control studies nested in cohorts (4%) [100][101][102].…”

Section: Description Of the Selected Articlesmentioning

confidence: 99%

“…48,50,63,67,70,95,97,100,103,104,106,[118][119][120][121][122][123]. Environmental factors were examined in association with gene expression profiling in four studies (5%)[65,71,78,108].…”

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confidence: 99%

A Scoping Review on the Characteristics of Human Exposome Studies

2019

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Embraced as a breaking through methodological framework, the exposome is accompanied by novel exposure assessment methods and data processing tools or models. However, systematic mapping of the landscape of exposome studies, including their characteristics, components, tools and language has not been done so far. We conducted a scoping review to answer the question: "Which main domains of the human exposome have been included in the literature and which metrics of exposure(s)/ outcome(s) have been used?" We performed a comprehensive search of human studies containing the word "exposom*" and published up to March 8, 2019. We screened 1133 records and 82 studies were included in the analysis. Most studies took place in Europe. Data analysis showed the non-systematic use of the exposome term. Most studies had a longitudinal design (n = 30, 37%), were conducted on adults (n = 40, 51%), and had a clearly defined health outcome in methodology (n = 48, 61%). Omics tools, such as metabolomics were used in 38 studies (49%), while environment-wide association analysis was used in 9 studies (11%). Thirty-seven (48%) studies included all three exposome domains (general external, specific external and internal) while 33 (42%) studies included two. Despite the large number of environmental components that comprise each of the exposome domains, only a subset has been currently studied. An optimized consideration of the components from all exposome domains, as well as the standardization of the exposure and outcome assessment methods is warranted to advance the utility of the human exposome concept.

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Human exposure to airborne pollen and relationships with symptoms and immune responses: Indoors versus outdoors, circadian patterns and meteorological effects in alpine and urban environments

Cited by 49 publications

References 49 publications

Climate Change and Pollen Allergies

Climate Change and Pollen Allergies

Aerobiology in South Africa: A new hope!

A Scoping Review on the Characteristics of Human Exposome Studies

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