Human cardiac imaging at 3 T using phased array coils

Noeske, Ralph; Rhein, Karl‐Heinz; Rinneberg, H.

doi:10.1002/1522-2594(200012)44:6<978::aid-mrm22>3.3.co;2-0

Cited by 52 publications

(88 citation statements)

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“…Specifically the pre-contrast T1 values for myocardium are approximately 850 ms at 1.5 T and 1,100 ms at 3 T [3]. A myocardial peak concentration of GD-DTPA of 0.75 mmol has been shown to yield myocardial T1 values of 235 and 275 ms at 1.5 T and 3 T, respectively.…”

Section: Discussionmentioning

confidence: 94%

“…Another potential advantage of myocardial stress perfusion imaging at 3 T is prolongation of the T1 relaxation in the range of 29 to 43% compared to 1.5 T [3,25], which can be expected to improve the conspicuity of T1-shortening contrast agents. Specifically the pre-contrast T1 values for myocardium are approximately 850 ms at 1.5 T and 1,100 ms at 3 T [3].…”

Section: Discussionmentioning

confidence: 99%

“…Sequence types for first-pass perfusion imaging at 3 T We chose a saturation recovery GE sequence combined with parallel imaging (TFE-SENSE) in our 3-T study, as this sequence is more robust to susceptibility artifacts and offresonance effects, which increase at higher field strengths [27] compared to b-SSFP and EPI sequences [3,29,30]. A further advantage of a saturation recovery GE sequence in comparison to b-SSFP is lower RF power deposition, which may have fewer conflicts with specific absorption rate (SAR) restrictions at 3 T [3,31].…”

Section: Discussionmentioning

confidence: 99%

“…A further advantage of a saturation recovery GE sequence in comparison to b-SSFP is lower RF power deposition, which may have fewer conflicts with specific absorption rate (SAR) restrictions at 3 T [3,31]. The rationale for our imaging protocol was to utilize the expected increase of SNR at 3 T to allow increased spatial resolution.…”

Section: Discussionmentioning

confidence: 99%

“…Cardiac magnetic resonance imaging at 3 T allows acquisition of images with higher signal-to-noise and contrast-to-noise ratios resulting in an improvement in performance for many cardiac MR applications in comparison to 1.5 T [1][2][3][4][5][6]. A recently published study demonstrated a significantly higher signal-to-noise ratio and myocardial enhancement ratio in first pass myocardial perfusion imaging at 3 T compared to 1.5 T [6].…”

Section: Introductionmentioning

confidence: 99%

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High-resolution myocardial stress perfusion at 3 T in patients with suspected coronary artery disease

et al. 2007

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To implement a high-resolution first-pass myocardial perfusion imaging protocol (HRPI) at 3 T, and to evaluate the feasibility, image quality and accuracy of this approach prospectively in patients with suspected CAD. We hypothesized that utilizing the gain in SNR at 3 T to increase spatial resolution would reduce partial volume effects and subendocardial dark rim artifacts in comparison to 1.5 T. HRPI studies were performed on 60 patients using a segmented k-space gradient echo sequence (in plane resolution 1.97 x 1.94 mm(2)). Semiquantitative assessment of dark rim artifacts was performed for the stress studies on a slice-by-slice basis. Qualitative visual analysis was compared to quantitative coronary angiography (QCA) results; hemodynamically significant CAD was defined as stenosis >or=70% at QCA. Dark rim artifacts appeared in 108 of 180 slices (average extent 1.3 +/- 1.2 mm representing 11.8 +/- 10.8% of the transmural myocardial thickness). Sensitivity, specifity, and test accuracy for the detection of significant CAD were 89%,79%, and 85%. HRPI studies at 3 T are feasible in a clinical setting, providing good image quality and high accuracy for detection of significant CAD. The presence of dark rim artifacts does not appear to represent a diagnostic problem when using a HRPI approach.

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Section: Discussionmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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High-resolution myocardial stress perfusion at 3 T in patients with suspected coronary artery disease

et al. 2007

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In vitro validation of phase‐contrast flow measurements at 3 T in comparison to 1.5 T: Precision, accuracy, and signal‐to‐noise ratios

Lotz

Döker

Noeske³

et al. 2005

Magnetic Resonance Imaging

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Purpose:To evaluate the signal-to-noise ratio (SNR), precision, and accuracy of phase-contrast flow measurements at 3 T with the help of an in vitro model and to compare the results with data from two 1.5-T scanners. Materials and Methods:Using an identical setup of a laminar flow model and sequence parameters, measurements were done at one 3-T and at two 1.5-T systems. Precision, accuracy, and SNR were obtained for velocity encodings ranging from 55 up to 550 cm -1 . SNRs were calculated from the magnitude as well as the flow encoded images.Results: Precision and accuracy for the in vitro flow model were similarly high in all scanners with no significant difference. For velocity encodings from 55 cm -1 up to 550 cm -1 , the SNR in magnitude as well as phase encoded images of the 3-T measurements was approximately 2.5 times higher than the SNR obtained from the two 1.5-T systems. Conclusion:Even without optimization for the 3-T environment, flow measurements show the same high accuracy and precision as is known from clinical 1.5-T scanners. The superior SNR at 3 T will allow further improvements in temporal and spatial resolution. This will be of interest for small-size vessels like coronary arteries or for slow diastolic flow patterns.

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Improved artery delineation in dual‐stack coronary magnetic resonance angiography using parallel imaging at 3 T

Huber

Kozerke

Boesiger

2005

Magnetic Resonance Imaging

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Purpose: To improve vessel sharpness and T2 preparation (T2Prep) in dual-stack three-dimensional coronary magnetic resonance angiography (MRA) by shortening the time delays between the magnetization preparation pulses and the imaging stacks using sensitivity encoding (SENSE) at 3 T. Materials and Methods:By combining dual-stack threedimensional coronary MRA with the parallel imaging technique SENSE at 3 T, the acquisition duration of each threedimensional imaging stack was shortened by a factor of 2. The proposed technique was implemented and tested in experiments with a moving phantom and in measurements on six healthy volunteers. Results:The time delay between the navigator, T2Prep, and second imaging stack was reduced by 37%, relative to conventional dual-stack angiography without parallel imaging. This enabled the achievement of comparable highvessel sharpness values for the left and the right coronary arteries relative to values known from conventional singlestack three-dimensional coronary MRA at 3 T. Conclusion:Parallel imaging allows for improved vessel visualization in dual-stack coronary MRA, given shorter temporal delays between navigator, T2Prep, and the actual image acquisitions, and thus considerably facilitates simultaneous acquisition of high-resolution angiograms of the left and right coronary systems. CORONARY MAGNETIC RESONANCE angiography (MRA) performed during free breathing and with respiratory navigator gating for real-time motion compensation has shown to be a promising technique for the visualization of potential coronary artery disease (1). The limited scan efficiency by the short data acquisition window of relative intrinsic cardiac rest during middiastole (2) and a respiratory gating efficiency of about 50% can be considered drawbacks of this approach. A single three-dimensional acquisition thus takes about 10 minutes. With two three-dimensional scans to cover both the left and the right coronary arterial systems, the total examination time, including planning and additional localizer scans, can easily exceed 45 minutes.An improvement in scan efficiency and a reduction of scan time can be achieved by the simultaneous acquisition of multiple independent three-dimensional image stacks, covering the main vessels of both coronary systems, as proposed by Manke et al (3). Since the two independent stacks are measured consecutively during mid-diastole, the overall data acquisition time within one cardiac cycle is prolonged by a factor of 2, relative to a conventional single-stack approach (4). Thus, conventional dual-stack angiography is more sensitive to artifacts by cardiac and respiratory motion. In addition, only one respiratory navigator is measured prior to the acquisition of the first three-dimensional stack, and the determined diaphragmatic displacement is used to subsequently calculate positional corrections for both successively sampled imaging stacks. This potentially violates previous findings stating that a short time delay between the navigator acquisition and the actual scanni...

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Human cardiac imaging at 3 T using phased array coils

Cited by 52 publications

References 0 publications

High-resolution myocardial stress perfusion at 3 T in patients with suspected coronary artery disease

High-resolution myocardial stress perfusion at 3 T in patients with suspected coronary artery disease

In vitro validation of phase‐contrast flow measurements at 3 T in comparison to 1.5 T: Precision, accuracy, and signal‐to‐noise ratios

Improved artery delineation in dual‐stack coronary magnetic resonance angiography using parallel imaging at 3 T

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