Human Biochemical Development

Gaull, Gerald E.; Hamosh, Margit; Hommes, F. A.

doi:10.1007/978-1-4613-2101-9_5

Cited by 1 publication

(2 citation statements)

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“…In fact, even in A. V. Hill (16) predicted that as animals increased in preparations of fetal mitochondria, there is very little size, body height would scale to body mass to the onedifference in pathways of oxidative phosphorylation third power and VO 2max would scale to body mass to the compared with mature systems (13). Our mean value for the work efficiency (29%) was not different from values two-thirds power.…”

Section: Discussioncontrasting

confidence: 48%

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Aerobic parameters of exercise as a function of body size during growth in children

Cooper¹,

Weiler-Ravell²,

Whipp³

et al. 1984

Journal of Applied Physiology

368

263

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To examine the relationship between body weight in children and aerobic parameters of exercise, we determined the anaerobic threshold (AT), maximum O2 uptake (VO2max), work efficiency, and response time for O2 uptake (RT-VO2) in 109 healthy children (51 girls and 58 boys, range 6-17 yr old) using a cross-sectional study design. Gas exchange during exercise was measured breath by breath. The protocol consisted of cycle ergometry and a linearly increasing work rate (ramp) to the limit of the subject's tolerance. Both AT and VO2max increased systematically with body weight, whereas work efficiency and RT-VO2 were virtually independent of body size. The ratio of AT to VO2max decreased slightly with age, and its mean value was 60%. AT scaled to body weight to the power of 0.92, not significantly different from the power of 1.01 for VO2max. Thus both the AT and the VO2max increase in a highly ordered manner with increasing size, and as judged by AT/VO2max, the onset of anaerobic metabolism during exercise occurred at a relatively constant proportion of the overall limit of the gas transport system. We conclude that in children cardiorespiratory responses to exercise are regulated at optimized values despite overall change in body size during growth.

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Section: Discussioncontrasting

confidence: 48%

“…For each child, a suitable slope was chosen based on our own initial studies. In general, for children from 6 to 9 yr of age, the ramp was 10 W/min; from [10][11][12][13]15 W/min; and from M-17, 20 W/min. For certain adolescents who were deemed to be quite fit by history, ramp slopes as high as 40 W/min were chosen.…”

Section: Methodsmentioning

confidence: 99%